The application of urinary proteomics for the detection of biomarkers of kidney diseases

S Jiang, Y Wang, Z Liu - Urine Proteomics in Kidney Disease Biomarker …, 2015 - Springer
Urine is a biological material that can be easily obtained in the clinic. The identification of
proteins excreted in urine provides useful biological information about the kidney as well as …

Understanding glomerular diseases through proteomics

E Mavrogeorgis, H Mischak, J Beige… - Expert Review of …, 2021 - Taylor & Francis
Introduction Chronic kidney disease is avery common and complex chronic disease.
Uncovering the pathological patterns of CKD on the molecular level of bio-fluids and tissue …

Proteomic analysis of renal diseases: unraveling the pathophysiology and biomarker discovery

V Thongboonkerd - Expert Review of Proteomics, 2005 - Taylor & Francis
Current biomedical applications of proteomics have been conducted with four main
objectives: to better understand the normal biology and physiology of cells, microorganisms …

Urine proteomics and biomarkers in renal disease

MJ Kim, AH Frankel, FWK Tam - Nephron experimental nephrology, 2011 - karger.com
The application of urine proteomics is a useful approach to the study of the proteins involved
in healthy and diseased kidneys and may provide a noninvasive approach to assess …

Clinical proteomics: application at the bedside

EF Petricoin, LA Liotta - Proteomics in Nephrology, 2004 - karger.com
The post-genome era of molecular medicine is moving to proteomics. The function of
proteins is directly tied to the microecology of the cell and surrounding structures. The …

Advances in urinary proteome analysis and biomarker discovery

D Fliser, J Novak, V Thongboonkerd… - Journal of the …, 2007 - journals.lww.com
Noninvasive diagnosis of kidney diseases and assessment of the prognosis are still
challenges in clinical nephrology. Definition of biomarkers on the basis of proteome …

Biomarker discovery in glomerular diseases using urinary proteomics

V Thongboonkerd - PROTEOMICS–Clinical Applications, 2008 - Wiley Online Library
Renal biopsy remains the gold standard test for definitive diagnosis of glomerular diseases.
This invasive procedure; however, has a potential risk for serious complications and is …

Quantification of molecular heterogeneity in kidney tissue by targeted proteomics

KJR Hoyer, S Dittrich, MP Bartram, MM Rinschen - Journal of proteomics, 2019 - Elsevier
Renal diseases are driven by alterations in the entity of proteins within the kidney, at the
level of single cells, nephron subunits (such as glomerulus and tubule), tissues and body …

Renal and urinary proteomics: current applications and challenges

V Thongboonkerd, P Malasit - Proteomics, 2005 - Wiley Online Library
During the past few years, proteomics has been extensively applied to various fields of
medicine including nephrology. Current applications of renal and urinary proteomics are to …

Current status of renal and urinary proteomics: ready for routine clinical application?

V Thongboonkerd - Nephrology Dialysis Transplantation, 2010 - academic.oup.com
Renal and urinary proteomics are among the most rapidly growing subdisciplines of
proteomics applied to biomedical research. The rapid growth of this field is evidenced by an …