Body fluid protein-based biomarkers carry the hope of improving patient management in
diabetes by enabling more accurate and earlier detection of diabetic kidney disease (DKD) …

Recent progress in proteomic analysis and strategies for the identification of clinically useful
biomarkers in biofluids has led to the identification of urine as an excellent non-invasive …

Diabetic nephropathy is a major complication of diabetes and remains a common health
problem worldwide. It is the dominant cause of incident end-stage renal disease. Currently …

More and more patients worldwide suffer from end-stage renal disease which often is
secondary to diabetes (eg 36.9% of all US patients with end-stage renal disease have a …

Proteomics has emerged as a powerful technology to decipher biological processes. One of
the main goals of proteomics is the identification of biomarkers for diseases from tissues and …

The last decade has seen a surge in publications describing novel biomarkers for early
detection of diabetic nephropathy (DN), but as yet none have outperformed albuminuria in …

Urinary proteomic biomarkers have emerged as clinically relevant variables. First studies
involving several hundred individuals indicate a potential added benefit of urinary proteomic …

Exponential technologies double in power or processing speed every year, whereas their
cost halves. Deception and disruption are two key stages in the development of exponential …

Proteomics has long been considered an ideal platform, and urine an ideal source for
biomarker discovery in human autoimmune kidney diseases. A number of studies have …

Serum is an ideal biological sample that contains an archive of information due to the
presence of a variety of proteins released by diseased tissue, and serum proteomics has …