Urinary proteomics and molecular determinants of chronic kidney disease: possible link to proteases
S Filip, C Pontillo, J Peter Schanstra… - Expert review of …, 2014 - Taylor & Francis
Chronic kidney disease (CKD) is the gradual decrease in renal function. Currently available
biomarkers are effective only in detecting late stage CKD. Biomarkers of early stage CKD …
biomarkers are effective only in detecting late stage CKD. Biomarkers of early stage CKD …
Proteomics and autoimmune kidney disease
BH Rovin, JB Klein - Clinical immunology, 2015 - Elsevier
Proteomics has long been considered an ideal platform, and urine an ideal source for
biomarker discovery in human autoimmune kidney diseases. A number of studies have …
biomarker discovery in human autoimmune kidney diseases. A number of studies have …
Proteomic technologies for the identification of disease biomarkers in serum: advances and challenges ahead
Serum is an ideal biological sample that contains an archive of information due to the
presence of a variety of proteins released by diseased tissue, and serum proteomics has …
presence of a variety of proteins released by diseased tissue, and serum proteomics has …
Expanding the proteome two‐dimensional gel electrophoresis reference map of human renal cortex by peptide mass fingerprinting
F Magni, C Sarto, C Valsecchi, S Casellato… - …, 2005 - Wiley Online Library
Proteomics methodologies hold great promise in basic renal research and clinical
nephrology. The classical approach for proteomic analysis couples two‐dimensional gel …
nephrology. The classical approach for proteomic analysis couples two‐dimensional gel …
Proteomic strategies for biomarker identification: progress and challenges.
ET Fung, GL Wright Jr, EA Dalmasso - Current opinion in molecular …, 2000 - europepmc.org
The simplest definition of a biomarker is a molecule that indicates an alteration in physiology
from normal. A more practical definition of a biomarker would require clinical utility of this …
from normal. A more practical definition of a biomarker would require clinical utility of this …
[HTML][HTML] Proteomics and disease revisited: the challenge of providing proteomic tools into clinical practice
TE Fehniger, G Marko-Varga - Journal of Proteome Research, 2010 - ACS Publications
Low-density lipoprotein. Alanine transaminase. Troponin I. Alpha-1-antitrypsin. Clinicians
throughout the world rely on standardized laboratory reference values of proteins to …
throughout the world rely on standardized laboratory reference values of proteins to …
Proteogenomics: key driver for clinical discovery and personalized medicine
Proteogenomics is a multi-omics research field that has the aim to efficiently integrate
genomics, transcriptomics and proteomics. With this approach it is possible to identify new …
genomics, transcriptomics and proteomics. With this approach it is possible to identify new …
Urine proteomics in clinical applications: technologies, principal considerations and clinical implementation.
The technology platforms for proteome analysis have advanced considerably over the last
few years. Due to these improvements the number of studies on the analysis of the …
few years. Due to these improvements the number of studies on the analysis of the …
Clinical proteomics: Closing the gap from discovery to implementation
Clinical proteomics, the application of proteome analysis to serve a clinical purpose,
represents a major field in the area of proteome research. Over 1000 manuscripts on this …
represents a major field in the area of proteome research. Over 1000 manuscripts on this …
Challenges of genomics and proteomics in nephrology
S Stojnev, M Pejcic, Z Dolicanin, LJ Velickovic… - Renal failure, 2009 - Taylor & Francis
An increasing number of patients suffering from renal diseases and limitations in standard
diagnostic and therapeutic approaches has created an intense interest in applying …
diagnostic and therapeutic approaches has created an intense interest in applying …