Immunopathogenesis of respiratory syncytial virus bronchiolitis

BL Bennett, RP Garofalo, SG Cron… - The Journal of …, 2007 - academic.oup.com
Background. The objective of this study was to elucidate the relation between respiratory
syncytial virus (RSV) infection and cytokine/chemokine concentrations, as well as the impact …

[HTML][HTML] Evaluation of viral load in infants hospitalized with bronchiolitis caused by respiratory syncytial virus

C Scagnolari, F Midulla, C Selvaggi… - Medical microbiology …, 2012 - Springer
The relationship between viral load, disease severity and antiviral immune activation in
infants suffering from respiratory syncytial virus (RSV)-associated bronchiolitis has not been …

Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease

P Sheeran, H Jafri, C Carubelli… - The Pediatric …, 1999 - journals.lww.com
Background. Respiratory syncytial virus (RSV) is the most common cause of lower
respiratory tract disease in infants. The role of inflammatory mediators in the pathogenesis of …

Respiratory syncytial virus bronchiolitis: Disease severity, interleukin‐8, and virus genotype

RL Smyth, KJ Mobbs, U O'Hea, D Ashby… - Pediatric …, 2002 - Wiley Online Library
In infants with respiratory syncytial virus (RSV) bronchiolitis, we investigated whether
disease severity is associated with the genotype of the infecting virus, or with the infant's …

What is the clinical relevance of respiratory syncytial virus bronchiolitis?: findings from a multi-center, prospective study

E Bamberger, I Srugo, B Abu Raya, E Segal… - European journal of …, 2012 - Springer
Acute bronchiolitis (AB) is caused primarily by respiratory syncytial virus (RSV). Recent
laboratory tools have implicated a variety of other pathogens; however, their clinical …

Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis

JP Legg, IR Hussain, JA Warner… - American journal of …, 2003 - atsjournals.org
We examined the in vivo immune response of infants to natural respiratory syncytial virus
(RSV) infection through analysis of cytokine levels in nasal lavage fluid and stimulated …

Chemokines and inflammation in the nasal passages of infants with respiratory syncytial virus bronchiolitis

TL Noah, SS Ivins, P Murphy, I Kazachkova… - Clinical …, 2002 - Elsevier
This study measured chemokines in nasal lavage fluids (NLF) from infants with respiratory
syncytial virus (RSV) bronchiolitis, defined by lung hyperinflation and wheezing …

Impaired immune response in severe human lower tract respiratory infection by respiratory syncytial virus

CL Larrañaga, SL Ampuero… - The Pediatric …, 2009 - journals.lww.com
Background: Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory
infection in infants. The immune response plays a leading role in the severity of the disease …

Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases

TP Welliver, JL Reed… - The Pediatric infectious …, 2008 - journals.lww.com
Respiratory syncytial virus (RSV) and influenza virus are common causes of infantile lower
respiratory tract infection (LRTI). It is widely believed that both viral replication and …

Novel inflammatory markers, clinical risk factors and virus type associated with severe respiratory syncytial virus infection

CM Tabarani, CA Bonville, M Suryadevara… - The Pediatric …, 2013 - journals.lww.com
Background: Virus-induced inflammation contributes to respiratory syncytial virus (RSV)
pathogenesis. We sought to determine the specific mediators that are associated with more …