[HTML][HTML] Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study
TS Voss, MH Vendelbo, U Kampmann, SB Pedersen… - Diabetologia, 2017 - Springer
Aims/hypothesis The aims of this study were to determine the role of lipolysis in
hypoglycaemia and define the underlying intracellular mechanisms. Methods Nine healthy …
hypoglycaemia and define the underlying intracellular mechanisms. Methods Nine healthy …
Mechanisms of insulin resistance after insulin-induced hypoglycemia in humans: the role of lipolysis
P Lucidi, P Rossetti, F Porcellati, S Pampanelli… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Changes in glucose metabolism occurring during counterregulation are, in part,
mediated by increased plasma free fatty acids (FFAs), as a result of hypoglycemia-activated …
mediated by increased plasma free fatty acids (FFAs), as a result of hypoglycemia-activated …
[HTML][HTML] Insulin-mediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance
JWE Jocken, GH Goossens, H Boon, RR Mason… - Diabetologia, 2013 - Springer
Aims/hypothesis Impaired regulation of lipolysis and accumulation of lipid intermediates may
contribute to obesity-related insulin resistance and type 2 diabetes mellitus. We investigated …
contribute to obesity-related insulin resistance and type 2 diabetes mellitus. We investigated …
[HTML][HTML] Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent …
TS Voss, MH Vendelbo, U Kampmann, SB Pedersen… - Diabetologia, 2019 - Springer
Aims/hypothesis Lack of insulin and infection/inflammation are the two most common causes
of diabetic ketoacidosis (DKA). We used insulin withdrawal followed by insulin …
of diabetic ketoacidosis (DKA). We used insulin withdrawal followed by insulin …
The role of intramyocellular lipids during hypoglycemia in patients with intensively treated type 1 diabetes
E Bernroider, A Brehm, M Krssak… - The Journal of …, 2005 - academic.oup.com
Context: Endocrine defensive mechanisms provide for energy supply during hypoglycemia.
Intramyocellular lipids (IMCL) were recently shown to contribute to energy supply during …
Intramyocellular lipids (IMCL) were recently shown to contribute to energy supply during …
Adipocyte lipolysis and insulin resistance
P Morigny, M Houssier, E Mouisel, D Langin - Biochimie, 2016 - Elsevier
Obesity-induced insulin resistance is a major risk factor for the development of type 2
diabetes. Basal fat cell lipolysis (ie, fat cell triacylglycerol breakdown into fatty acids and …
diabetes. Basal fat cell lipolysis (ie, fat cell triacylglycerol breakdown into fatty acids and …
Inhibition of lipolysis in Type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates
EL Lim, KG Hollingsworth, FE Smith… - Clinical …, 2011 - portlandpress.com
Suppression of lipolysis by acipimox is known to improve insulin-stimulated glucose
disposal, and this is an important phenomenon. The mechanism has been assumed to be …
disposal, and this is an important phenomenon. The mechanism has been assumed to be …
Insulin regulation of lipolysis in nondiabetic and IDDM subjects
MD Jensen, M Caruso, V Heiling, JM Miles - Diabetes, 1989 - Am Diabetes Assoc
To determine whether insulin regulation of lipolysis is abnormal in subjects with poorly
controlled insulin-dependent diabetes mellitus (IDDM), free-fatty acid flux ([1-14C] palmitate) …
controlled insulin-dependent diabetes mellitus (IDDM), free-fatty acid flux ([1-14C] palmitate) …
[PDF][PDF] Adipose tissue lipolysis revisited (again!): lactate involvement in insulin antilipolytic action
D Langin - Cell metabolism, 2010 - cell.com
Adipose Tissue Lipolysis Revisited (Again!): Lactate Involvement in Insulin Antilipolytic Action
Page 1 Cell Metabolism Previews Adipose Tissue Lipolysis Revisited (Again!): Lactate …
Page 1 Cell Metabolism Previews Adipose Tissue Lipolysis Revisited (Again!): Lactate …
Augmented effect of short-term pulsatile versus continuous insulin delivery on lipid metabolism but similar effect on whole-body glucose metabolism in obese subjects
O Schmitz, SB Pedersen, A Mengel, N Pørksen, J Bak… - Metabolism, 1994 - Elsevier
The present study was designed to examine the effect of pulsatile versus continuous insulin
delivery on glucose and lipid metabolism in insulin-resistant subjects. Six obese women …
delivery on glucose and lipid metabolism in insulin-resistant subjects. Six obese women …