Aims/hypothesis NEFA play a key role in the setting of insulin resistance and
hyperinsulinaemia, which are both features of the prediabetic state. In addition to the direct …

Elevated plasma free fatty acid (FFA) concentrations as seen in obesity, insulin resistance,
and type 2 diabetes are partly caused by impaired inhibition of intracellular lipolysis in …

The increased risk of hypoglycemia during intensified treatment of type 1 diabetes mellitus
(T1DM) patients, who have a deficient glucagon secretory response, is largely attributed to …

(F= 3.70, p= 0.003). The circulating levels of free fatty acids in-creased about three-fold in
parallel to the in situ lipolytic re-sponse (F= 2.98, p= 0.025). The same lipolytic response was …

As an important energy reservoir, adipose tissue maintains lipid balance and regulates
energy metabolism. When the body requires energy, adipocytes provide fatty acids to …

Aims/hypothesis. To estimate non-esterified fatty acids kinetics in patients with Type II (non-
insulin-dependent) diabetes mellitus and obese subjects in the postabsorptive state and …

Aims/hypothesis. Both patients with Type II (non-insulin-dependent) diabetes mellitus and
normoglycaemic, insulin resistant subjects were shown to have an increased lipid content in …

During the fasting state, insulin reduces nonesterified fatty acid (NEFA) appearance in the
systemic circulation mostly by suppressing intracellular lipolysis in the adipose tissue. In the …

Context: Large fat cell size is linked to type 2 diabetes risk and may involve an enhanced
rate of adipocyte lipolysis causing elevated levels of fatty acids. Objective: Our objective was …

Hypoglycemia, a major side effect of intensive glucose-lowering therapy, was recently linked
to increased cardiovascular risk in patients with diabetes. Whether increased circulating free …