Catecholamine and insulin control of lipolysis in subcutaneous adipose tissue during long-term diet-induced weight loss in obese women

K Koppo, M Siklová-Vitková… - American Journal …, 2012 - journals.physiology.org
The aim of this study was to investigate the evolution of the adrenergic and insulin-mediated
regulation of lipolysis during different phases of a 6-mo dietary intervention. Eight obese …

[引用][C] Control of lipolysis and its relevance to development of obesity in man

P Amer - Diabetes/metabolism reviews, 1988 - Wiley Online Library
Obesity is a major health problem in the western world and its frequency is steadily
increasing. Although overeating and physical inactivity are probably the major causes of …

Fasting-mediated alteration studies in insulin action on lipolysis and lipogenesis in obese women

P Arner, P Engfeldt - American Journal of Physiology …, 1987 - journals.physiology.org
The effects of fasting on insulin-induced antilipolysis and lipogenesis were investigated in
vitro in isolated human fat cells of 11 obese females. Glycerol release and lipogenesis were …

Effect of obesity on susceptibility to fatty acid–induced peripheral tissue insulin resistance

YT Kruszynska, JM Olefsky, JP Frias - Metabolism, 2003 - Elsevier
Elevation of plasma nonesterified fatty acid (NEFA) levels has been shown to impair the
actions of insulin on peripheral glucose uptake and suppression of hepatic glucose output …

[PDF][PDF] Weight gain and impaired glucose metabolism in women are predicted by inefficient subcutaneous fat cell lipolysis

P Arner, DP Andersson, J Bäckdahl, I Dahlman… - Cell metabolism, 2018 - cell.com
Adipocyte mobilization of fatty acids (lipolysis) is instrumental for energy expenditure.
Lipolysis displays both spontaneous (basal) and hormone-stimulated activity. It is unknown if …

Insulin action in morbid obesity: a focus on muscle and adipose tissue

P Mitrou, SA Raptis, G Dimitriadis - Hormones, 2013 - Springer
The aim of this review is to summarize the mechanisms underlying insulin resistance in
morbid obesity. Glucose regulation by insulin depends on the suppression of endogenous …

Effect of gender on lipid-induced insulin resistance in obese subjects

B Vistisen, LI Hellgren, T Vadset… - European journal of …, 2008 - academic.oup.com
Objective In obese subjects, chronically elevated plasma concentrations of non-esterified
fatty acids (NEFAs) exert a marked risk to contract insulin resistance and subsequently type …

Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes

G Perseghin, G Lattuada, F De Cobelli, A Esposito… - Diabetologia, 2005 - Springer
Aims/hypothesis Insulin resistance may be associated with ectopic fat accumulation
potentially determined by reduced lipid oxidation. In patients with type 1 diabetes peripheral …

Effects of 10 days of endurance exercise training on the suppression of whole body and regional lipolysis by insulin

RC Hickner, SB Racette, EF Binder… - The Journal of …, 2000 - academic.oup.com
The aim of this study was to evaluate in premenopausal women (10 sedentary obese
women) the effects of 10 days of exercise on the suppression of whole body and regional …

Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure

S Nielsen, N Møller, JS Christiansen… - Diabetes, 2001 - Am Diabetes Assoc
Stimulation of lipolysis and the induction of resistance to insulin's actions on glucose
metabolism are well-recognized effects of growth hormone (GH). To evaluate whether these …