The aim of this study was to identify inflammatory mediators of potential clinical relevance in
synovial fluid (SF) samples of patients with knee osteoarthritis (OA). Therefore, radiographic …

Background One of the sources of knee pain in osteoarthritis (OA) is believed to be related
to local chronic inflammation of the knee joints, which involves the production of …

The purpose of this pilot study was to evaluate the cytokine profile of human knee synovial
fluid and correlate this with the subject's degree of articular cartilage degradation …

Objective: The objective of this study is to compare inflammatory cytokine levels in primary
knee osteoarthritis (OA) patients and healthy controls. Methods: A total of 32 knee OA …

Background Inflammatory mediators in the synovial fluid (SF) play critical roles in the
initiation and development of pain in knee osteoarthritis (KOA). However, data for …

Background Inflammation is associated with the onset and progression of osteoarthritis in
multiple joints. It is well known that mechanical properties differ between different joints …

Osteoarthritis (OA) is a debilitating degenerative joint disease particularly affecting
weightbearing joints within the body, principally the hips and knees. Current radiographic …

Objective To evaluate the role of immune cells and their effector cytokines in the
pathogenesis and progression of knee osteoarthritis (OA) in matched OA synovial fluid (SF) …

Little is known about local and systemic biomarkers in relation to synovitis and pain in end-
stage osteoarthritis (OA) patients. We investigated the associations between the novel …

Objective Increasing evidence has shown the involvement of the innate immune system and
inflammatory response in osteoarthritis (OA) pathogenesis; however, anterior cruciate …