T-cell neoplasms are a group of heterogeneous neoplasms that present a challenge in
management. Accurate diagnosis and classification are necessary for proper treatment. This …

Unconventional T cells and innate lymphoid cells (ILCs) make up a heterogeneous set of
cells that characteristically show prompt responses toward specific antigens …

T cells are major players in the adaptive immune response to pathogens. They express
clonally distributed, highly polymorphic antigen receptors that enable them to recognize cell …

T-cell lymphomas represent a heterogeneous group of neoplasms that encompass
considerable clinical, morphologic, and immunophenotypic variation. The diagnosis of T-cell …

Classical mycosis fungoides and Sezary syndrome are part of a larger spectrum of
cutaneous T cell lymphomas. Widespread infiltration of the skin, early invovlement of the T …

T-cell lymphomas are a heterogeneous group of rare malignancies with overlapping clinical,
immunologic, and histologic features. Recent advances in our understanding of T-cell …

The rearranging antigen receptor genes of lymphoid cells serve as unique clonal markers of
lymphoid neoplasms. Gene rearrangement analysis is a highly sensitive and reproducible …

By combining immunologic investigations using various techniques with cytomorphologic
and enzyme cytochemical analyses, substantial advances have been made in the …

In this review, we discuss the structure, organization and activation of the immunoglobulin
(Ig) and T cell receptor (TCR) genes and the use of DNA probes derived from these genes …

Patients with B-cell malignancies are often immunosuppressed and have defective T-cell
function in vitro. In addition they frequently have unusual T-cell populations in the peripheral …