Heterozygous mutations of the human FOXP2 transcription factor gene cause the best-
described examples of monogenic speech and language disorders. Acquisition of proficient …

Heterozygous mutations in FOXP2, which encodes a forkhead transcription factor, have
been shown to cause developmental verbal dyspraxia and language impairment. FOXP2 …

Mutations in the human FOXP2 gene cause impaired speech development and linguistic
deficits, which have been best characterised in a large pedigree called the KE family. The …

The creative “reiterative” powers of human language and thought appear to have evolved
from brain mechanisms initially adapted for motor control. Humans can form a potentially …

Abstract Mental retardation affects 2‐3% of the population and shows a high heritability.
Neurodevelopmental disorders that include pronounced impairment in language and …

FOXP2 is a forkhead transcription factor implicated in developmental verbal dyspraxia, a
human speech and language disorder. FOXP2 is expressed in complex patterns during …

That speech and language are innate capacities of the human brain has long been widely
accepted, but only recently has an entry point into the genetic basis of these remarkable …

Lessons from 1 million genomes Page 1 www.nature.com/nrg ReseaRch highlights 592 |
oCToBeR 2018 | volume 19 ORIGINAl ARtICle Chandra, V. et al. Social regulation of insulin …

Rare disruptions of FOXP2 have been strongly implicated in deficits in language
development. Research over the past decade has suggested a role in the formation of …

Human Genetics: The Evolving Story of FOXP2 Page 1 7. Graybiel, AM, and Ragsdale, CW,
Jr. (1978). Histochemically distinct compartments in the striatum of human, monkeys, and …