Altered social behavior in mice carrying a cortical Foxp2 deletion

VP Medvedeva, MA Rieger, B Vieth… - Human molecular …, 2019 - academic.oup.com
Genetic disruptions of the forkhead box transcription factor FOXP2 in humans cause an
autosomal-dominant speech and language disorder. While FOXP2 expression pattern are …

Conserved role of Drosophila melanogaster FoxP in motor coordination and courtship song

KJ Lawton, TL Wassmer, DL Deitcher - Behavioural brain research, 2014 - Elsevier
FoxP2 is a highly conserved vertebrate transcription factor known for its importance in
human speech and language production. Disruption of FoxP2 in several vertebrate models …

Modified sound-evoked brainstem potentials in Foxp2 mutant mice

S Kurt, M Groszer, SE Fisher, G Ehret - Brain research, 2009 - Elsevier
Heterozygous mutations of the human FOXP2 gene cause a developmental disorder
involving impaired learning and production of fluent spoken language. Previous …

FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution

W Enard - Current opinion in neurobiology, 2011 - Elsevier
PURPOSE OF THE REVIEW: A reduced dosage of the transcription factor FOXP2 leads to
speech and language impairments probably owing to deficits in cortical and subcortical …

Deciphering the genetic basis of speech and language disorders

SE Fisher, CSL Lai, AP Monaco - Annual review of …, 2003 - annualreviews.org
▪ Abstract A significant number of individuals have unexplained difficulties with acquiring
normal speech and language, despite adequate intelligence and environmental stimulation …

[HTML][HTML] A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment

R Lozano, A Vino, C Lozano, SE Fisher… - European journal of …, 2015 - nature.com
FOXP1 (forkhead box protein P1) is a transcription factor involved in the development of
several tissues, including the brain. An emerging phenotype of patients with protein …

Not the neocortex alone: other brain structures also contribute to speech and language

KR Gibson - 2011 - academic.oup.com
This article gives an overview on the various brain structures, other than neocortex,
contributing to speech and language. The regions of the avian brain which are considered …

Molecular cloning and developmental expression of foxP2 in zebrafish

JL Bonkowsky, CB Chien - Developmental Dynamics, 2005 - Wiley Online Library
Forkhead domain transcription factors are a large gene family with multiple roles in
development. FOXP2, a recently identified member of this family, has been shown to be …

Building bridges between genes, brains and language

SE Fisher - Birdsong, speech and language: Exploring the …, 2013 - books.google.com
It has been suspected for several decades that genetic factors contribute to speech and
language development/function, based primarily on indirect data from twin studies and …

First gene linked to speech identified

M Balter - 2001 - science.org
Plenty of animals can caw or roar or buzz, but only human beings can string a complex
series of sounds together into speech. Now a team of researchers has identified the first …