[HTML][HTML] Sarcopenia–Molecular mechanisms and open questions

P Wiedmer, T Jung, JP Castro, LCD Pomatto… - Ageing research …, 2021 - Elsevier
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …

Inflammaging: The ground for sarcopenia?

Z Liang, T Zhang, H Liu, Z Li, L Peng, C Wang… - Experimental …, 2022 - Elsevier
Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

New horizons in the pathogenesis, diagnosis and management of sarcopenia

AA Sayer, SM Robinson, HP Patel… - Age and …, 2013 - academic.oup.com
Sarcopenia is the age-related loss of skeletal muscle mass and function. It is now
recognised as a major clinical problem for older people and research in the area is …

[HTML][HTML] Redox signaling and sarcopenia: searching for the primary suspect

NA Foreman, AS Hesse, LL Ji - International journal of molecular sciences, 2021 - mdpi.com
Sarcopenia, the age-related decline in muscle mass and function, derives from multiple
etiological mechanisms. Accumulative research suggests that reactive oxygen species …

Mouse models of sarcopenia: classification and evaluation

W Xie, M He, D Yu, Y Wu, X Wang, S Lv… - Journal of cachexia …, 2021 - Wiley Online Library
Sarcopenia is a progressive and widespread skeletal muscle disease that is related to an
increased possibility of adverse consequences such as falls, fractures, physical disabilities …

[HTML][HTML] Biochemical pathways of sarcopenia and their modulation by physical exercise: a narrative review

MM Ziaaldini, E Marzetti, A Picca, Z Murlasits - Frontiers in medicine, 2017 - frontiersin.org
Aging is a complex process characterized by progressive multisystem derangement
predisposing individuals to increased risk of developing negative health outcomes …

[HTML][HTML] Autophagy in sarcopenia: Possible mechanisms and novel therapies

G Xie, H Jin, H Mikhail, V Pavel, G Yang, B Ji… - Biomedicine & …, 2023 - Elsevier
With global population aging, age-related diseases, especially sarcopenia, have attracted
much attention in recent years. Characterized by low muscle strength, low muscle quantity or …

[HTML][HTML] Molecular mechanism and pathogenesis of sarcopenia: An overview

A Picca, R Calvani - International journal of molecular sciences, 2021 - mdpi.com
Sarcopenia involves a progressive age-related decline of skeletal muscle mass and
strength/function [1]. This muscle loss is associated with increased risk of adverse health …

[HTML][HTML] A multifactorial approach for sarcopenia assessment: a literature review

R Supriya, KP Singh, Y Gao, F Li, F Dutheil, JS Baker - Biology, 2021 - mdpi.com
Simple Summary Sarcopenia is characterized by an accelerated decline in skeletal muscle
mass and strength, which results in poor quality of life, disability, and death. In the literature …

[HTML][HTML] Sarcopenia: Molecular regulatory network for loss of muscle mass and function

J Wu, P Ding, H Wu, P Yang, H Guo, Y Tian… - Frontiers in …, 2023 - frontiersin.org
Skeletal muscle is the foundation of human function and plays a key role in producing
exercise, bone protection, and energy metabolism. Sarcopenia is a systemic disease, which …