Biomarkers of physical frailty and sarcopenia: coming up to the place?

A Picca, R Calvani, M Cesari, F Landi… - International journal of …, 2020 - mdpi.com
Physical frailty and sarcopenia (PF&S) recapitulates all the hallmarks of aging and has
become a focus in geroscience. Factors spanning muscle-specific processes (eg …

Multimodal diagnostic approaches to advance precision medicine in sarcopenia and frailty

DH Lynch, HB Spangler, JR Franz, RL Krupenevich… - Nutrients, 2022 - mdpi.com
Sarcopenia, defined as the loss of muscle mass, strength, and function with aging, is a
geriatric syndrome with important implications for patients and healthcare systems …

[HTML][HTML] Sarcopenic obesity: an emerging public health problem

T Ji, Y Li, L Ma - Aging and disease, 2022 - ncbi.nlm.nih.gov
Population aging and the obesity epidemic are important global public health problems that
pose an unprecedented threat to the physical and mental health of the elderly and health …

[HTML][HTML] Rodent model of muscular atrophy for sarcopenia study

KW Baek, YK Jung, JS Kim, JS Park… - Journal of bone …, 2020 - ncbi.nlm.nih.gov
The hallmark symptom of sarcopenia is the loss of muscle mass and strength without the
loss of overall body weight. Sarcopenia patients are likely to have worse clinical outcomes …

[HTML][HTML] Managing sarcopenia and its related-fractures to improve quality of life in geriatric populations

T Hida, A Harada, S Imagama, N Ishiguro - Aging and disease, 2014 - ncbi.nlm.nih.gov
Sarcopenia, an aging-induced generalized decrease in muscle mass, strength, and function,
is known to affect elderly individuals by decreasing mobile function and increasing frailty …

Sarcopenia, aging and prospective interventional strategies

TB Waltz, EM Fivenson, M Morevati, C Li… - Current Medicinal …, 2018 - ingentaconnect.com
Sarcopenia, or age-related muscle decline, occurs in most organisms and burdens both
human health and the healthcare system. As our population ages, additional options for …

Sarcopenia and frailty in older patients with diabetes mellitus

H Umegaki - Geriatrics & gerontology international, 2016 - Wiley Online Library
Sarcopenia is defined as age‐associated loss of muscle mass and function, and is
frequently accompanied by diabetes mellitus (DM) in older adults. Some of the mechanisms …

Sarcopenia: age-related skeletal muscle changes from determinants to physical disability

A Di Iorio, M Abate, D Di Renzo… - International journal …, 2006 - journals.sagepub.com
Human aging is characterized by skeletal muscle wasting, a debilitating condition which sets
the susceptibility for diseases that directly affect the quality of life and often limit life span …

Prevalence of depression in patients with sarcopenia and correlation between the two diseases: systematic review and meta‐analysis

Z Li, X Tong, Y Ma, T Bao, J Yue - Journal of cachexia …, 2022 - Wiley Online Library
Background Depression may be the most common cause of emotional distress later in life
and can significantly reduce the quality of life in elderly individuals. Sarcopenia is a …

Mediators and patterns of muscle loss in chronic systemic inflammation

S Pérez-Baos, I Prieto-Potin, JA Roman-Blas… - Frontiers in …, 2018 - frontiersin.org
Besides its primary function in locomotion, skeletal muscle (SKM), which represents up to
half of human's weight, also plays a fundamental homeostatic role. Through the secretion of …