False-positive amphetamine screen following a trazodone overdose

RJ Roberge, JR Luellen, S Reed - Journal of Toxicology: Clinical …, 2001 - Taylor & Francis
Urine drugs-of-abuse screening tests are routinely employed in many emergency
departments (ED) for evaluation of drug overdose. Crossreactivity can result in falsepositives …

ONTRAK TESTCUP: a novel, on-site, multi-analyte screen for the detection of abused drugs

J Towt, SCJ Tsai, MR Hernandez… - Journal of analytical …, 1995 - academic.oup.com
We developed a rapid, sensitive, and simple-to-use multi-analyte diagnostic device for the
detection of drugs of abuse in urine: the ONTRAK TESTCUP. No sample or reagent …

Adulterants causing false negatives in illicit drug testing.

SL Mikkelsen, KO Ash - Clinical Chemistry, 1988 - academic.oup.com
Illicit-drug users may attempt to falsify results by in vitro adulteration of specimens. We
investigated eight additives (NaCl, Visine, handsoap, Drano, bleach, vinegar, golden-seal …

Application of High-Resolution UPLC–MSE/TOF Confirmation in Forensic Urine Drug Screening by UPLC–MS/MS

TG Rosano, PY Ohouo, M Wood - Journal of analytical …, 2019 - academic.oup.com
The transition from presumptive (immunoassay) drug screening to definitive screening has
continued in the practice of analytical toxicology. Development of a ultra-performance liquid …

Adulteration of drugs-of-abuse specimens

A Dasgupta - Drugs of abuse: body fluid testing, 2005 - Springer
Persons abusing drugs attempt to adulterate urine specimens in order to beat drug testing.
Dilution of urine in vivo by consuming excess fluid and various detoxifying agents available …

Evaluation of detection techniques and laboratory proficiency in testing for drugs of abuse in urine: an external quality assessment scheme using clinically realistic …

JF Wilson, BL Smith, BL - Annals of clinical biochemistry, 1999 - journals.sagepub.com
Techniques for the detection of drugs of abuse were compared using data from 43 urine
samples distributed by the United Kingdom National External Quality Assessment Scheme …

Effect of urine adulterants on commercial drug abuse screening test strip results

I Rajšić, D Javorac, S Tatović, A Repić… - Archives of Industrial …, 2020 - sciendo.com
Immunochromatographic strips for urine drug screening tests (UDSTs) are common and very
suitable for drug abuse monitoring, but are also highly susceptible to adulterants kept in the …

Status of drugs-of-abuse testing in urine under blind conditions: an AACC study.

CS Frings, DJ Battaglia, RM White - Clinical Chemistry, 1989 - academic.oup.com
We report results of a blind study designed to determine the accuracy of drugs-of-abuse
testing in urine as done in 31 laboratories across the United States. The drugs studied were …

Lack of detection of new amphetamine-like drugs using conventional urinary immunoassays

A Begeman, EJF Franssen - Therapeutic Drug Monitoring, 2018 - journals.lww.com
Background: The number of reports of serious adverse effects and intoxication after the use
of the new drug 4-fluoroamphetamine (4-FA) increases. At the Emergency Department of the …

'False-positive'and 'false-negative'test results in clinical urine drug testing

GM Reisfield, BA Goldberger, RL Bertholf - Bioanalysis, 2009 - Taylor & Francis
The terms 'false-positive'and 'false-negative'are widely used in discussions of urine drug test
(UDT) results. These terms are inadequate because they are used in different ways by …