Background: Little is known about the role of WNT signalling in pathological processes
involving the urinary tract stroma. Here the impact of WNT signalling on bladder wall …

RESULTS: Wif-1 mRNA expression was significantly down-regulated in BT compared with
BM (p< O. OOI). We identified LOH at 12q14. 3 in only 5.6% of BTs. However, methylation of …

Urothelial carcinoma of bladder is the second most prevalent genitourinary disease. It is a
highly heterogeneous disease as it represents a spectrum of neoplasms, including non …

Background Bladder cancer, including urothelial carcinoma (UC), is the most common
malignancy of the urinary tract and the fourth most frequent cancer overall in men. Wnt5a, a …

Purpose To analyze the contribution of Wnt signaling pathway to bladder cancer growth in
order to identify suitable target molecules for therapy. Material and methods Expression of …

Once urinary bladder cancer (UBC) develops into muscle-invasive bladder cancer, its
mortality rate increases dramatically. However, the molecular mechanisms of UBC invasion …

The Wnt signaling pathway is involved in a wide range of embryonic patterning events and
maintenance of homeostasis in adult tissues. The pathological role of the Wnt pathway has …

Bladder cancer is the fourth most common cancer in men and the most common malignancy
of the urinary tract. Bladder cancers detected at an early stage have a very high five-year …

Background Recurrence and metastasis are the major problems of bladder urothelial
carcinoma, which mainly attribute to tumor cell stemness, epithelial-mesenchymal transition …

This study assessed the functional role of WNT genes and the association between WNT
signalling cascades and fibrosis in interstitial cystitis/bladder pain syndrome (IC/BPS) …