Anemia is defined by a deficiency of hemoglobin, an iron-rich protein that binds oxygen in
the blood. It can be due to multiple causes, either acquired or genetic. Alterations of genes …

Sideroblastic anemia is characterized by anemia with the emergence of ring sideroblasts in
the bone marrow. Ring sideroblasts are erythroblasts characterized by iron accumulation in …

Inherited disorders of iron metabolism : Current Opinion in Pediatrics Inherited disorders of iron
metabolism : Current Opinion in Pediatrics Log in or Register Subscribe to journalSubscribe Get …

Main disorders of iron metabolism Increased iron requirements, limited external supply, and
increased blood loss may lead to iron deficiency (ID) and iron deficiency anaemia. In chronic …

Congenital forms of sideroblastic anemia constitute a subset of uncommon disorders within
the wider spectrum of sideroblastic anemias, all of which are diagnosed by the presence of …

Iron is a vitally important element in mammalian metabolism because of its unsurpassed
versatility as a biologic catalyst. However, when not appropriately shielded or when present …

Background In the western world, 10–15% of women of child-bearing age suffer from iron-
deficiency anemia. Iron overload due to chronic treatment with blood transfusions or …

The sideroblastic anemias (SAs) are a group of inherited and acquired bone marrow
disorders defined by pathological iron accumulation in the mitochondria of erythroid …

Iron functions Iron is an essential micronutrient, as it is required for satisfactory erythropoietic
function, oxidative metabolism and cellular immune response. Iron physiology Absorption of …

Sideroblastic anemias are heterogeneous congenital and acquired disorders characterized
by anemia and the presence of ringed sideroblasts in the bone marrow. Congenital …