Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes cognitive
impairment. Major pathophysiological AD characteristics include numerous senile plaque …

Alzheimer's disease (AD) is a very common progressive neurodegenerative disorder
affecting the learning and memory abilities in the brain. Key findings from recent studies of …

Alzheimer's disease (AD) is a growing global threat to healthcare in the aging population. In
the USA alone, it is estimated that one in nine persons over the age of 65 years is living with …

The brain undergoes several anatomical, biochemical, and molecular changes during
aging, which subsequently result in downregulation of synaptic plasticity genes and decline …

In the brains of patients with Alzheimer's disease (AD) and transgenic AD mouse models,
astrocytes and microglia activated by amyloid-β (Aβ) contribute to the inflammatory process …

Sporadic Alzheimer's disease (SAD) is a slowly progressive neurological disorder that is the
most common form of dementia. Cholinergic system dysfunction and amyloid beta formation …

Histone acetylation has been shown to play a crucial role in memory formation, and histone
deacetylase (HDAC) inhibitor sodium butyrate (NaB) has been demonstrated to improve …

Background Epigenetic mechanisms such as post-translational histone acetylation are
increasingly recognized for their contribution to gene activation and silencing in the brain …

Epigenetic mechanisms such as post-translational histone modifications are increasingly
recognized for their contribution to gene activation and silencing in the brain. Histone …

Studies on the effective and safe therapeutic dosage of delta-9-tetrahydrocannabinol (THC)
for the treatment of Alzheimer's disease (AD) have been sparse due to the concern about …