Angiotensin I and II. Some early observations made at the Cleveland Clinic Foundation and recent discoveries relative to angiotensin II formation in human heart.

FM Bumpus - Hypertension, 1991 - Am Heart Assoc
The renin-angiotensin system originally was thought to be responsible for only renovascular
hypertension, but the development and use of various inhibitors of this system have …

Angiotensinogen: hormonal regulation and relative importance in the generation of angiotensin II

CF Deschepper - Kidney international, 1994 - Elsevier
Angiotensinogen: Hormonal regulation and relative importance in the generation of
angiotensin II. The production of angiotensinogen is controlled mainly by hormones that …

Regulation of angiotensin converting enzyme.

F Fyhrquist, C Grönhagen-Riska, L Hortling… - … : Official Journal of the …, 1983 - europepmc.org
Angiotensin converting enzyme (ACE; EC 3.4. 15.1), or kininase II, was studied in serum,
cultured endothelial cells from cord artery, in macrophages of humans, and in serum and …

Gene expression and tissue localization of the two isoforms of angiotensin I converting enzyme.

M Sibony, JM Gasc, F Soubrier, F Alhenc-Gelas… - …, 1993 - Am Heart Assoc
Angiotensin converting enzyme exists in two different isoforms, somatic and germinal,
whose respective distributions and intracellular localizations have not been precisely …

Angiotensinases restrict locally generated angiotensin II to the blood vessel wall

KF Hilgers, E Bingener, C Stumpf, DN Müller… - …, 1998 - Am Heart Assoc
We tested the hypothesis that angiotensinases limit the spillover of locally formed
angiotensin II into the circulation. The release of angiotensin peptides from isolated rat …

Renal tissue angiotensin II: response to infusions of angiotensin I and an angiotensin-converting enzyme inhibitor

G Reams, D Villarreal, Z Wu, JH Bauer - American journal of kidney …, 1993 - Elsevier
A procedure for the collection, processing, extraction, separation, and measurement of renal
tissue angiotensin II [ANG-(1–8)] is described. The arterial plasma and renal tissue …

The two homologous domains of human angiotensin I-converting enzyme are both catalytically active

L Wei, F Alhenc-Gelas, P Corvol, E Clauser - Journal of Biological …, 1991 - ASBMB
Molecular cloning of human endothelial angiotensin I-converting enzyme (kininase II; EC
3.4. 15.1)(ACE) has recently shown that the enzyme contains two large homologous …

Distribution and metabolism of angiotensin I and II in the blood vessel wall.

P Gohlke, P Bünning, T Unger - Hypertension, 1992 - Am Heart Assoc
The demonstration of all components of the renin-angiotensin system in vascular tissue has
raised questions as to the precise location of the local angiotensin II generation within the …

Human converting enzyme

EG Erdos, JT Gafford - … Hypertension. Part A: Theory and Practice, 1983 - Taylor & Francis
Angiotensin I converting enzyme (kininase II, peptidyl dipeptidase, ACE) was purified by
reverse immunoadsorption from a membrane fraction of the human kidney. ACE is very …

Differential regulation of vascular angiotensin I-converting enzyme in hypertension.

MS Fernandez-Alfonso, R Kreutz, K Zeh, Y Liu… - …, 1994 - Am Heart Assoc
The angiotensin I-converting enzyme (ACE) gene is found on the locus that has been linked
to high blood pressure after sodium loading in rats, so in the present study we investigated …