Molecular cloning of a new aquaporin superfamily in mammals: AQPX1 and AQPX2

K Ishibashi, M Kuwahara, Y Kageyama… - Molecular biology and …, 2000 - Springer
Currently, aquaporins (AQPs) are divided into two subfamilies: AQP1 group and AQP3
group. AQP1 group is water-selective AQP and has 6 members in mammals: AQPO, AQP1 …

Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution

K Liu, D Kozono, Y Kato, P Agre… - Proceedings of the …, 2005 - National Acad Sciences
Aquaporin (AQP) 6 belongs to the aquaporin water channel family. Unlike other aquaporins,
AQP6 functions not as a water channel but as an anion-selective channel. Single-channel …

[HTML][HTML] Aquaporin-11 containing a divergent NPA motif has normal water channel activity

K Yakata, Y Hiroaki, K Ishibashi, E Sohara… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Recently, two novel mammalian aquaporins (AQPs), AQPs 11 and 12, have been identified
and classified as members of a new AQP subfamily, the “subcellular AQPs”. In members of …

Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin

K Ishibashi, T Morinaga, M Kuwahara, S Sasaki… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Recently, a new member of aquaporins was reported as AQP10 [Biochem. Biophys. Res.
Commun. 287 (2001) 814], which is incompletely spliced to lose the sixth transmembrane …

Purification and functional characterization of aquaporin‐8

K Liu, H Nagase, CG Huang, G Calamita… - Biology of the …, 2006 - Wiley Online Library
Background information. Aquaporins (AQPs) are a family of channels permeable to water
and some small solutes. In mammals, 13 members (AQP0–AQP12) have been found. AQP8 …

Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channel

LM Chen, J Zhao, R Musa-Aziz… - American Journal …, 2010 - journals.physiology.org
The mammalian aquaporins AQP1, AQP4, and AQP5 have been shown to function not only
as water channels but also as gas channels. Zebrafish have two genes encoding an AQP1 …

The evolutionary aspects of aquaporin family

K Ishibashi, S Kondo, S Hara… - American Journal of …, 2011 - journals.physiology.org
Aquaporins (AQPs) were originally identified as channels facilitating water transport across
the plasma membrane. They have a pair of highly conserved signature sequences …

The distribution and function of aquaporins in the kidney: resolved and unresolved questions

T Matsuzaki, T Yaguchi, K Shimizu, A Kita… - Anatomical science …, 2017 - Springer
The membrane water channel aquaporin (AQP) family is composed of 13 isoforms in
mammals, eight of which are reportedly expressed in the kidney: AQP1, 2, 3, 4, 6, 7, 8, and …

Aquaporin water channels–from atomic structure to clinical medicine

P Agre, LS King, M Yasui, WB Guggino… - The Journal of …, 2002 - Wiley Online Library
The water permeability of biological membranes has been a longstanding problem in
physiology, but the proteins responsible for this remained unknown until discovery of the …

Aquaporins: phylogeny, structure, and physiology of water channels

JB Heymann, A Engel - Physiology, 1999 - journals.physiology.org
How water permeates cellular membranes and what this means for cell functioning and
several diseases are now emerging from the study of the aquaporins (AQPs), the water …