Naringin improves lipid metabolism in a tissue-engineered liver model of NAFLD and the underlying mechanisms

X Zhang, Y Zhang, W Gao, Z Guo, K Wang, S Liu… - Life Sciences, 2021 - Elsevier
Aims Nonalcoholic fatty liver disease (NAFLD) is a lipid metabolism disorder. Naringin (a
main active ingredient in Ganshuang granules) is a flavanone that has been demonstrated …

[HTML][HTML] Novel therapeutic potentials of taxifolin for obesity-induced hepatic steatosis, fibrogenesis, and tumorigenesis

T Inoue, B Fu, M Nishio, M Tanaka, H Kato, M Tanaka… - Nutrients, 2023 - mdpi.com
The molecular pathogenesis of nonalcoholic steatohepatitis (NASH) includes a complex
interaction of metabolic stress and inflammatory stimuli. Considering the therapeutic goals of …

Protective effects of plant-derived flavonoids on hepatic injury

L Wan, JG Jiang - Journal of Functional Foods, 2018 - Elsevier
Liver ailments have become one of the most health-threatening problems, looking for safe
and effective natural liver protection agents is one of future directions. Flavonoids are widely …

[HTML][HTML] n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD

D Vauzour, I Rodriguez-Ramiro, S Rushbrook… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults and at present no licensed
medication has been approved. Despite its complex patho-physiology, dietary strategies …

Nobiletin mitigates NAFLD via lipophagy and inflammation

X Yang, Y Deng, Y Tu, D Feng, W Liao - Food & Function, 2022 - pubs.rsc.org
Nonalcoholic fatty liver disease (NAFLD), an increasingly serious health issue around the
world, is characterized as a lipid metabolic disorder without any satisfactory treatment …

[HTML][HTML] The anti-inflammatory effect of Pien Tze Huang in non-alcoholic fatty liver disease

B Lian, L Cai, Z Zhang, F Lin, Z Li, X Zhang… - Biomedicine & …, 2022 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease that may
progress to nonalcoholic steatohepatitis (NASH), hepatic tissue fibrosis, liver cirrhosis, and …

[HTML][HTML] Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model

J Xiao, YP Ching, EC Liong, AA Nanji, ML Fung… - European Journal of …, 2013 - Springer
Purpose To investigate the hepato-protective properties and underlying mechanisms of
SAMC in a non-alcoholic fatty liver disease (NAFLD) rat model. Methods Female rats were …

Naringenin attenuates non‐alcoholic fatty liver disease by down‐regulating the NLRP3/NF‐κB pathway in mice

Q Wang, Y Ou, G Hu, C Wen, S Yue… - British Journal of …, 2020 - Wiley Online Library
Background and Purpose Naringenin, a flavonoid compound with strong anti‐inflammatory
activity, attenuated non‐alcoholic fatty liver disease (NAFLD) induced by a methionine …

Meta-analysis of traditional herbal medicine in the treatment of nonalcoholic fatty liver disease

H Peng, Y He, G Zheng, W Zhang, Z Yao… - Cellular and Molecular …, 2016 - cellmolbiol.org
Traditional Chinese herbal medicine (TCM) has been found effective for nonalcoholic fatty
liver disease (NAFLD) based on its unique theory system and substantial herb remedies …

[HTML][HTML] Chinese medicinal herbs targeting the gut–liver axis and adipose tissue–liver axis for non-alcoholic fatty liver disease treatments: the ancient wisdom and …

S Zhang, YT Wong, KY Tang, HY Kwan… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases
worldwide. The pathogenesis of NAFLD is complex. Frontline western medicines only …