Integrative transcriptomics and proteomics analyses to reveal the therapeutic effect and mechanism of Buxue Yimu Pills in medical-induced incomplete abortion rats

LL Zhang, F Sheng, Y Yang, YF Hu, W Li… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Medical abortions using mifepristone and misoprostol
have been approved in many countries for early pregnancy loss. Despite its high success …

[HTML][HTML] Chemical fingerprint analysis and ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry-based metabolomics study of the …

Y Zhang, W Li, TT Chen, Y Yang, MY Wu… - Frontiers in …, 2020 - frontiersin.org
Medical abortion is a common method to terminate an early pregnancy and often causes
serious complications such as abnormal uterine bleeding and endometritis. Buxue Yimu …

Buxue Yimu Pills improve angiogenesis and blood flow in experimental zebrafish and rat models

LL Zhang, F Sheng, Y He, Y Yang, YF Hu, W Li… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Buxue Yimu Pills (BYP) is a well-known
traditional Chinese medicine prescription which is clinical used in gynecology and …

[HTML][HTML] Uterine metabolomics reveals protection of Taohong Siwu decoction against abnormal uterine bleeding

Y Zhang, C Zuo, L Han, X Liu, W Chen… - Frontiers in …, 2020 - frontiersin.org
Incomplete abortion, a procedure for terminating pregnancy, will lead to abnormal uterine
bleeding (AUB), infections, and even death. Taohong Siwu decoction (TSD) is a traditional …

The Potential Mechanism of Zishen Yutai Pills against Threatened Abortion: An Approach Involving Network Pharmacology and Experimental Evidence

J Wang, X Liu, Y Zhang, S Lin, H Ma… - Evidence‐Based …, 2023 - Wiley Online Library
Threatened abortion (TA) is the most common complication in early pregnancy and is
caused by anxiety and depressive symptoms. The Zishen Yutai Pill (ZYP) is a traditional …

BushenHuoxue Recipe for the Treatment of Prethrombotic State of ACA‐Positive Recurrent Miscarriage via the Regulation of the PI3K‐AKT Signaling Pathway

X Yang, S Su, Q Ren, L Liu, J Li… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Although the Bushen Huoxue (BSHX) recipe is commonly used for the effective
treatment of the prethrombotic state of recurrent abortions, its mechanism of action is …

Deciphering the intervention mechanism of Taohong Siwu Decoction following the abnormal uterine bleeding rats based on serum metabolic profiles

C Zuo, Y Zhang, J Wang, L Han, C Peng… - Journal of Pharmaceutical …, 2019 - Elsevier
Abnormal uterine bleeding (AUB), one of the most significant characters of incomplete
abortion, is a widespread phenomenon in gynecological that put a woman into a terrible …

[HTML][HTML] Zishen Yutai pills restore fertility in premature ovarian failure through regulating arachidonic acid metabolism and the ATK pathway

L Dang, Y Dong, C Zhang, B Su, N Ning, S Zhou… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The Zishen Yutai pills (ZYP), a Chinese medicinal
formulation derived from the Qing Dynasty prescription “Shou Tai pills", have been …

[HTML][HTML] Metabolomic mechanism and pharmacodynamic material basis of Buxue Yimu pills in the treatment of anaemia in women of reproductive age

G Ying-Ying, W Yan-Fang, D Yan, Z Su-Ying… - Frontiers in …, 2023 - frontiersin.org
Objective: To explore the pharmacological basis and mechanism of Buxue Yimu pills (BYP)
in the treatment of anaemia in women from the perspective of metabolomics and network …

Mechanism of cryptotanshinone to improve endocrine and metabolic functions in the endometrium of PCOS rats

YC Liu, JW Wang, J Li, Y Guo, FJ Han, WH Lu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cryptotanshinone is the main bioactive component of
Salvia miltiorrhiza, with various mechanisms of action, including antioxidant, anti …