Background Functional abnormalities, mostly involving functionally specialized subsystems,
have been associated with disorders of emotion regulation such as bipolar disorder (BD) …

Introduction: The fronto-limbic network has been suggested as a key circuitry in the
pathophysiology and maintenance of bipolar disorder. In the past decade, a disrupted …

Because of our classification system limitations for defining psychiatric disorders and
understanding their physiopathology, a new research area based on dimensions has …

Longitudinal studies of biological domains in bipolar disorder (BD) are crucial in determining
if such baseline changes are progressive. We reviewed reported studies of longitudinal …

BackgroundExploring the neural basis related to different mood states is a critical issue for
understanding the pathophysiology underlying mood switching in bipolar disorder (BD), but …

Bipolar disorder (BD) and borderline personality (BPD) disorder share clinical features such
as emotional lability and poor interpersonal functioning but the course of illness and …

Importance Individuals with bipolar disorder (BD) experience cognitive and emotional
dysfunctions. Various brain circuits are implicated in BD but have not been investigated in a …

Data from the imaging literature have led to suggestions that permanent structural brain
changes may be associated with bipolar disorder. Individuals diagnosed with bipolar …

Background Reward circuit dysfunction underlies the pathogenesis of bipolar disorder (BD).
This study aims to investigate whether nucleus accumbens (NAcc) and ventromedial …

Bipolar disorder (BP) is among the top ten most disabling illnesses worldwide. This review
includes findings from recent studies employing functional neuroimaging to examine …