[HTML][HTML] New insights into the interplay between autophagy and oxidative and endoplasmic reticulum stress in neuronal cell death and survival

Y Gao, C Wang, D Jiang, G An, F Jin… - Frontiers in Cell and …, 2022 - frontiersin.org
Autophagy is a dynamic process that maintains the normal homeostasis of cells by digesting
and degrading aging proteins and damaged organelles. The effect of autophagy on neural …

Autophagy as a homeostatic mechanism in response to stress conditions in the central nervous system

C Gerónimo-Olvera, L Massieu - Molecular Neurobiology, 2019 - Springer
Autophagy is considered a major bulk degradation system that helps cells to counteract
different intracellular and extracellular stress signals. Several protein complexes integrate …

Autophagy as a cellular stress response mechanism in the nervous system

N Peker, D Gozuacik - Journal of molecular biology, 2020 - Elsevier
Cells of an organism face with various types of insults during their lifetime. Exposure to
toxins, metabolic problems, ischaemia/reperfusion, physical trauma, genetic diseases …

Targeting endoplasmic reticulum stress and autophagy as therapeutic approaches for neurological diseases

A Thangaraj, S Sil, A Tripathi, ET Chivero… - International review of …, 2020 - Elsevier
Neurological diseases are multifactorial, devastating diseases that are causative for various
neurodegenerative disorders. Emerging evidence points that accumulation of unfolded …

Autophagy and apoptosis cascade: which is more prominent in neuronal death?

R Gupta, RK Ambasta, P Kumar - Cellular and Molecular Life Sciences, 2021 - Springer
Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …

ROS and autophagy: interactions and molecular regulatory mechanisms

L Li, J Tan, Y Miao, P Lei, Q Zhang - Cellular and molecular neurobiology, 2015 - Springer
Reactive oxygen species (ROS) and antioxidant ingredients are a series of crucial signaling
molecules in oxidative stress response. Under some pathological conditions such as …

Roles of autophagy in oxidative stress

HR Yun, YH Jo, J Kim, Y Shin, SS Kim… - International journal of …, 2020 - mdpi.com
Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by
lysosomal degradation pathways. Autophagy is implicated in various biological processes …

Intersection between redox homeostasis and autophagy: Valuable insights into neurodegeneration

H Park, J Kim, C Shin, S Lee - Antioxidants, 2021 - mdpi.com
Autophagy, a main degradation pathway for maintaining cellular homeostasis, and redox
homeostasis have recently been considered to play protective roles in neurodegenerative …

Crosstalk between endoplasmic reticulum stress response and autophagy in human diseases

J Kwon, J Kim, KI Kim - Animal cells and systems, 2023 - Taylor & Francis
Cells activate protective mechanisms to overcome stressful conditions that threaten cellular
homeostasis, including imbalances in calcium, redox, and nutrient levels. Endoplasmic …

Autophagy triggers endoplasmic reticulum stress and C/EBP homologous protein-mediated apoptosis in OGD/R-treated neurons in a caspase-12-independent …

Y Tian, L Wang, Z Qiu, Y Xu… - Journal of …, 2021 - journals.physiology.org
We reported that a high level of autophagy was initiated by oxygen-glucose deprivation
(OGD) and was maintained in neurons even after oxygen-glucose deprivation followed by …