Cross-neutralization of four paramyxoviruses by a human monoclonal antibody
Broadly neutralizing antibodies reactive against most and even all variants of the same viral
species have been described for influenza and HIV-1 (ref.). However, whether a neutralizing …
species have been described for influenza and HIV-1 (ref.). However, whether a neutralizing …
Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus
Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) are two closely
related viruses that cause bronchiolitis and pneumonia in infants and the elderly 1, with a …
related viruses that cause bronchiolitis and pneumonia in infants and the elderly 1, with a …
[HTML][HTML] Cross-protective antibodies against common endemic respiratory viruses
M Cabán, JV Rodarte, M Bibby, MD Gray… - Nature …, 2023 - nature.com
Respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and human
parainfluenza virus types one (HPIV1) and three (HPIV3) can cause severe disease and …
parainfluenza virus types one (HPIV1) and three (HPIV3) can cause severe disease and …
[HTML][HTML] Engineering, structure and immunogenicity of the human metapneumovirus F protein in the postfusion conformation
V Más, L Rodriguez, E Olmedillas, O Cano… - PLoS …, 2016 - journals.plos.org
Human metapneumovirus (hMPV) is a paramyxovirus that is a common cause of
bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) …
bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) …
Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo
ND Ulbrandt, H Ji, NK Patel, JM Riggs… - Journal of …, 2006 - Am Soc Microbiol
Human metapneumovirus (hMPV) is a recently described member of the Paramyxoviridae
family/Pneumovirinae subfamily and shares many common features with respiratory …
family/Pneumovirinae subfamily and shares many common features with respiratory …
[HTML][HTML] Individual contributions of the human metapneumovirus F, G, and SH surface glycoproteins to the induction of neutralizing antibodies and protective immunity
MH Skiadopoulos, S Biacchesi, UJ Buchholz… - Virology, 2006 - Elsevier
We evaluated the individual contributions of the three surface glycoproteins of human
metapneumovirus (HMPV), namely the fusion F, attachment G, and small hydrophobic SH …
metapneumovirus (HMPV), namely the fusion F, attachment G, and small hydrophobic SH …
The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness
MH Skiadopoulos, S Biacchesi, UJ Buchholz… - Journal of …, 2004 - Am Soc Microbiol
The growth properties and antigenic relatedness of the CAN98-75 (CAN75) and the CAN97-
83 (CAN83) human metapneumovirus (HMPV) strains, which represent the two distinct …
83 (CAN83) human metapneumovirus (HMPV) strains, which represent the two distinct …
[HTML][HTML] A newly discovered human pneumovirus isolated from young children with respiratory tract disease
BG Van den Hoogen, JC de Jong, J Groen, T Kuiken… - Nature medicine, 2001 - nature.com
From 28 young children in the Netherlands, we isolated a paramyxovirus that was identified
as a tentative new member of the Metapneumovirus genus based on virological data …
as a tentative new member of the Metapneumovirus genus based on virological data …
In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10
A Manrique, P Rusert, B Joos, M Fischer… - Journal of …, 2007 - Am Soc Microbiol
Recently, passive immunization of human immunodeficiency virus (HIV)-infected individuals
with monoclonal antibodies (MAbs) 2G12, 2F5, and 4E10 provided evidence of the in vivo …
with monoclonal antibodies (MAbs) 2G12, 2F5, and 4E10 provided evidence of the in vivo …
The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice
R Alvarez, RA Tripp - Journal of virology, 2005 - Am Soc Microbiol
Human metapneumovirus (HMPV), recently identified in isolates from children hospitalized
with acute respiratory tract illness, is associated with clinical diagnosis of pneumonia …
with acute respiratory tract illness, is associated with clinical diagnosis of pneumonia …