Nuclear factor erythroid 2–related factor2 (Nrf2) is a redox-sensitive transcription factor. Its
activation by low dietary intake of ligands leads to antioxidant effects (eustress), while pro …

With obesity rates reaching epidemic proportions, more studies concentrated on reducing
the risk and treating this epidemic are vital. Redox stress is an important metabolic regulator …

Inflammation is a protective process for life that aims to restore body homeostasis by
targeting the injury and by inducing repair mechanisms. This process can also become …

Polyunsaturated fatty acids (PUFA) play essential roles in cell membrane structure and
physiological processes including signal transduction, cellular metabolism and tissue …

Obesity is a growing problem that threatens the health and welfare of a large proportion of
the human population. The n-3 polyunsaturated fatty acids (PUFA) are dietary factors that …

Oxidative stress (OS) is a pathological status that occurs when the body's balance between
oxidants and antioxidant defense systems is broken, which can promote the development of …

Background Nrf2 is a transcription factor that induces the expression of several proteins with
antioxidant properties such as sestrin2 (Sesn2) and is therefore considered as the major …

Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults and at present no licensed
medication has been approved. Despite its complex patho-physiology, dietary strategies …

Obesity and its complications have become serious global health concerns recently and
increasing work has been carried out to explicate the underlying mechanism of the disease …

The nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that responds to
oxidative stress by binding to the antioxidant response element (ARE) in the promoter of …