The role of n-3 PUFA-derived fatty acid derivatives and their oxygenated metabolites in the modulation of inflammation
Notwithstanding the ongoing debate on their full potential in health and disease, there is
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …
Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy
L Shen, Y Yang, T Ou, CCC Key, SH Tong… - Journal of lipid …, 2017 - ASBMB
Dietary PUFAs reduce atherosclerosis and macrophage inflammation, but how nucleotide-
binding oligomerization domain leucine-rich repeat-containing receptor protein (NLRP3) …
binding oligomerization domain leucine-rich repeat-containing receptor protein (NLRP3) …
Polyunsaturated fatty acids: conversion to lipid mediators, roles in inflammatory diseases and dietary sources
JL Harwood - International Journal of Molecular Sciences, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …
N-3 long-chain polyunsaturated fatty acid supplementation significantly reduces liver oxidative stress in high fat induced steatosis
R Valenzuela, A Espinosa, D González-Mañán… - 2012 - journals.plos.org
Omega-3 (n-3) long-chain polyunsaturated fatty acids (n-3 LCPUFA) are associated with
several physiological functions, suggesting that their administration may prevent non …
several physiological functions, suggesting that their administration may prevent non …
Endogenous Generation and Signaling Actions of Omega‐3 Fatty Acid Electrophilic Derivatives
C Cipollina - BioMed research international, 2015 - Wiley Online Library
Dietary omega‐3 polyunsaturated fatty acids (PUFAs) are beneficial for a number of
conditions ranging from cardiovascular disease to chronic airways disorders …
conditions ranging from cardiovascular disease to chronic airways disorders …
Narrative Review of n-3 Polyunsaturated Fatty Acid Supplementation upon Immune Functions, Resolution Molecules and Lipid Peroxidation
GP Zaloga - Nutrients, 2021 - mdpi.com
Fish oil supplementation is commonplace in human nutrition and is being used in both
enteral and parenteral formulations during the treatment of patients with a large variety of …
enteral and parenteral formulations during the treatment of patients with a large variety of …
A lipidomic study on the regulation of inflammation and oxidative stress targeted by marine ω-3 PUFA and polyphenols in high-fat high-sucrose diets
G Dasilva, M Pazos, E García-Egido… - The Journal of …, 2017 - Elsevier
The ability of polyphenols to ameliorate potential oxidative damage of ω-3 PUFAs when they
are consumed together and then, to enhance their potentially individual effects on metabolic …
are consumed together and then, to enhance their potentially individual effects on metabolic …
Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages
R Varì, M D'Archivio, C Filesi, S Carotenuto… - The Journal of …, 2011 - Elsevier
Protocatechuic acid (PCA) is a main metabolite of anthocyanins, whose daily intake is much
higher than that of other polyphenols. PCA has biological effects, eg, it induces the …
higher than that of other polyphenols. PCA has biological effects, eg, it induces the …
Biological and pathophysiological roles of end-products of DHA oxidation
VP Yakubenko, TV Byzova - … et Biophysica Acta (BBA)-Molecular and Cell …, 2017 - Elsevier
Background Polyunsaturated fatty acids (PUFA) are known to be present and/or enriched in
vegetable and fish oils. Among fatty acids, n-3 PUFA are generally considered to be …
vegetable and fish oils. Among fatty acids, n-3 PUFA are generally considered to be …
The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation
The emerging role of Nrf2 as an effector of metabolic and longevity signals offers new
therapeutic perspectives. The potential impact of pharmacological manipulation of Nrf2 …
therapeutic perspectives. The potential impact of pharmacological manipulation of Nrf2 …