Polyunsaturated fatty acids (n-3 PUFAs) are long-chain polyunsaturated fatty acids with 18,
20 or 22 carbon atoms, which have been found able to counteract cardiovascular diseases …

A 48-h incubation of cultured human fibroblasts with 5× 10− 5 M oleic acid or
polyunsaturated fatty acids (PUFA) from the (n-6)(linoleic, γ-linolenic and arachidonic acids) …

Maintenance of a balanced redox state within the cell is of critical importance to a wide
variety of biological systems. Nuclear factor erythroid-derived 2-like 2 (Nrf2) is a critical …

There is some evidence to support the toxicity of polyunsaturated fatty acids (PUFAs) and
their oxidative products, suggesting their involvement in the pathogenesis of different …

Inflammatory bowel disease (IBD) is an immune-mediated gut dysfunction, which might also
be associated with an inflammatory phenotype in the liver. It is known that the nutritional …

Context Increased free fatty acids (FFAs) levels, typical in obesity condition, can contribute to
systemic lipotoxicity and inflammation adversely influencing Inflammatory Bowel Disease …

Background We previously reported on the anti-obesogenic and anti-inflammatory effects
associated with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in our diet-induced …

Chronic inflammation contributes toward the pathogenesis of numerous diseases including,
but not limited to, obesity, autoimmunity, cardiovascular diseases, and cancers. The …

Abstract α-Linolenic acid (ALA) is an essential fatty acid and the precursor for long-chain n-3
PUFA. However, biosynthesis of n-3 PUFA is limited in a Western diet likely due to an …

Increased amounts of reactive oxygen species (ROS) have been implicated in many
pathological conditions, including cancer. The major machinery that the cell employs to …