Crosstalk between Gut Microbiota and Epigenetic Markers in Obesity Development: Relationship between Ruminococcus, BMI, and MACROD2/SEL1L2 Methylation

F Salas-Perez, TS Assmann, O Ramos-Lopez… - Nutrients, 2023 - mdpi.com
Changes in gut microbiota composition and in epigenetic mechanisms have been proposed
to play important roles in energy homeostasis, and the onset and development of obesity …

Gut microbiota composition is associated with the global DNA methylation pattern in obesity

B Ramos-Molina, L Sánchez-Alcoholado… - Frontiers in …, 2019 - frontiersin.org
Objective: Obesity and obesity-related metabolic diseases are characterized by gut
microbiota and epigenetic alterations. Recent insight has suggested the existence of a …

Gut microbiota as an epigenetic regulator: pilot study based on whole-genome methylation analysis

H Kumar, R Lund, A Laiho, K Lundelin, RE Ley… - MBio, 2014 - Am Soc Microbiol
The core human gut microbiota contributes to the developmental origin of diseases by
modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic …

Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes

W Guo, Z Zhang, L Li, X Liang, Y Wu, X Wang… - Pharmacological …, 2022 - Elsevier
Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …

[HTML][HTML] Diet, gut microbiota, and obesity: links with host genetics and epigenetics and potential applications

A Cuevas-Sierra, O Ramos-Lopez, JI Riezu-Boj… - Advances in …, 2019 - Elsevier
Diverse evidence suggests that the gut microbiota is involved in the development of obesity
and associated comorbidities. It has been reported that the composition of the gut microbiota …

The epigenetic connection between the gut microbiome in obesity and diabetes

M Sharma, Y Li, ML Stoll, TO Tollefsbol - Frontiers in genetics, 2020 - frontiersin.org
Metabolic diseases are becoming an alarming health issue due to elevated incidences of
these diseases over the past few decades. Various environmental factors are associated …

Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome

S Ussar, NW Griffin, O Bezy, S Fujisaka, S Vienberg… - Cell metabolism, 2015 - cell.com
Obesity, diabetes, and metabolic syndrome result from complex interactions between
genetic and environmental factors, including the gut microbiota. To dissect these …

Gut microbiota: a contributing factor to obesity

SM Harakeh, I Khan, T Kumosani, E Barbour… - Frontiers in Cellular …, 2016 - frontiersin.org
Obesity, a global epidemic of the modern era, is a risk factor for cardiovascular diseases
(CVD) and diabetes. The pervasiveness of obesity and overweight in both developed as …

The microbiome, epigenome, and diet in adults with obesity during behavioral weight loss

EB Hill, IR Konigsberg, D Ir, DN Frank, P Jambal… - Nutrients, 2023 - mdpi.com
Obesity has been linked to the gut microbiome, epigenome, and diet, yet these factors have
not been studied together during obesity treatment. Our objective was to evaluate …

Role of gut microbiota in the aetiology of obesity: proposed mechanisms and review of the literature

MJ Khan, K Gerasimidis, CA Edwards… - Journal of …, 2016 - Wiley Online Library
The aetiology of obesity has been attributed to several factors (environmental, dietary,
lifestyle, host, and genetic factors); however none of these fully explain the increase in the …