Gut microbiome and obesity: a plausible explanation for obesity

C Sanmiguel, A Gupta, EA Mayer - Current obesity reports, 2015 - Springer
Obesity is a multifactorial disorder that results in excessive accumulation of adipose tissue.
Although obesity is caused by alterations in the energy consumption/expenditure balance …

High-fat diet determines the composition of the murine gut microbiome independently of obesity

MA Hildebrandt, C Hoffmann, SA Sherrill–Mix… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: The composition of the gut microbiome is affected by host
phenotype, genotype, immune function, and diet. Here, we used the phenotype of RELMβ …

[HTML][HTML] Mendelian randomization analysis reveals causal effects of the human gut microbiota on abdominal obesity

Q Xu, SS Zhang, RR Wang, YJ Weng, X Cui… - The Journal of …, 2021 - Elsevier
Background Although recent studies have revealed an association between the composition
of the gut microbiota and obesity, whether specific gut microbiota cause obesity has not …

Specific gut microbiota features and metabolic markers in postmenopausal women with obesity

LK Brahe, E Le Chatelier, E Prifti, N Pons… - Nutrition & …, 2015 - nature.com
Background: Gut microbial gene richness and specific bacterial species are associated with
metabolic risk markers in humans, but the impact of host physiology and dietary habits on …

A pilot study to examine the association between human gut microbiota and the host's central obesity

SH Koo, CW Chu, JJC Khoo, M Cheong, GH Soon… - JGH …, 2019 - Wiley Online Library
Background and Aim Perturbance in the composition of human gut microbiota has been
associated with metabolic disorders such as obesity, diabetes mellitus, and insulin …

Effect of the Gut microbiota on obesity and its underlying mechanisms: an update

LL Qian, HT Li, L Zhang, QC Fang, WP Jia - Biomedical and Environmental …, 2015 - Elsevier
Obesity has become one of the most prevalent health issues of our time. According to a
2012 WHO report, around 3.4 million adults die each year as a result of being overweight or …

Application of NMR-based metabolomics to the study of gut microbiota in obesity

R Calvani, E Brasili, G Pratico, F Sciubba… - Journal of clinical …, 2014 - journals.lww.com
Lifestyle habits, host gene repertoire, and alterations in the intestinal microbiota concur to
the development of obesity. A great deal of research has recently been focused on …

Unraveling the mystery: a Mendelian randomized exploration of gut microbiota and different types of obesity

S Liu, F Li, Y Cai, L Ren, L Sun, X Gang… - Frontiers in Cellular and …, 2024 - frontiersin.org
Background Numerous studies have demonstrated the influence of gut microbiota on the
development of obesity. In this study, we utilized Mendelian randomization (MR) analysis to …

[HTML][HTML] Obesity and the gut microbiome: Striving for causality

ITW Harley, CL Karp - Molecular metabolism, 2012 - Elsevier
The gut microbiome has been proposed to play a causal role in obesity. Here, we review the
historical context for this hypothesis, highlight recent key findings, and critically discuss …

Gut microbiota phenotypes of obesity

MA Stanislawski, D Dabelea, LA Lange… - NPJ biofilms and …, 2019 - nature.com
Obesity is a disease with a complex etiology and variable prevalence across different
populations. While several studies have reported gut microbiota composition differences …