Gut microbiota, host genetics and diet interact to affect the risk of developing obesity and the metabolic syndrome

C Greenhill - Nature reviews Endocrinology, 2015 - nature.com
New research has shed light on the complex interactions that underlie the development of
obesity and the metabolic syndrome.“We were able to identify interactions between host …

The role of gut microbiota in human obesity: recent findings and future perspectives

A Tagliabue, M Elli - Nutrition, Metabolism and Cardiovascular Diseases, 2013 - Elsevier
AIMS: In recent years, gut microbiota have gained a growing interest as an environmental
factor that may affect the predisposition toward adiposity. In this review, we describe and …

The gut microbiome and its role in obesity

CD Davis - Nutrition today, 2016 - journals.lww.com
The human body is host to a vast number of microbes, including bacterial, fungal, and
protozoal microorganisms, which together constitute our microbiota. Evidence is emerging …

[HTML][HTML] Gut microbiome and metabolome profiles associated with high-fat diet in mice

JK Jo, SH Seo, SE Park, HW Kim, EJ Kim, JS Kim… - Metabolites, 2021 - mdpi.com
Obesity can be caused by microbes producing metabolites; it is thus important to determine
the correlation between gut microbes and metabolites. This study aimed to identify gut …

Distinct gut microbiota induced by different fat-to-sugar-ratio high-energy diets share similar pro-obesity genetic and metabolite profiles in prediabetic mice

K Shan, H Qu, K Zhou, L Wang, C Zhu, H Chen, Z Gu… - Msystems, 2019 - Am Soc Microbiol
Gut microbiota play important roles in host metabolism, especially in diabetes. However,
why different diets lead to similar diabetic states despite being associated with different …

Evaluating causality of gut microbiota in obesity and diabetes in humans

AS Meijnikman, VE Gerdes, M Nieuwdorp… - Endocrine …, 2018 - academic.oup.com
The pathophysiology of obesity and obesity-related diseases such as type 2 diabetes
mellitus (T2DM) is complex and driven by many factors. One of the most recently identified …

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development

DH Kulkarni, B Rusconi, AN Floyd, EL Joyce… - Gut …, 2023 - Taylor & Francis
Obesity and the metabolic syndrome are complex disorders resulting from multiple factors
including genetics, diet, activity, inflammation, and gut microbes. Animal studies have …

[HTML][HTML] Effect of antibiotic growth promoters on intestinal microbiota in food animals: a novel model for studying the relationship between gut microbiota and human …

J Lin - Frontiers in microbiology, 2011 - frontiersin.org
As more children and adults become obese in the US and other countries,
obesityassociated diseases are becoming more prevalent worldwide (Poirier et al., 2006) …

The microbiome and obesity: is obesity linked to our gut flora?

F Tsai, WJ Coyle - Current gastroenterology reports, 2009 - Springer
The human gut is a lush microbial ecosystem containing about 100 trillion microorganisms,
whose collective genome, the microbiome, contains 100-fold more genes than the entire …

Role of the gut microbiome in the pathogenesis of obesity and obesity-related metabolic dysfunction

KE Bouter, DH van Raalte, AK Groen, M Nieuwdorp - Gastroenterology, 2017 - Elsevier
The potential role of intestinal microbiota in the etiology of various human diseases has
attracted massive attention in the last decade. As such, the intestinal microbiota has been …