Generation and functional significance of CXC chemokines for neutrophil-induced liver injury during endotoxemia

RB Dorman, JS Gujral, ML Bajt… - American Journal …, 2005 - journals.physiology.org
Generation and functional significance of CXC chemokines for neutrophil-induced liver
injury during endotoxemia. Am J Physiol Gastrointest Liver Physiol 288: G880–G886, 2005 …

Critical role of CXC chemokines in endotoxemic liver injury in mice

X Li, D Klintman, Q Liu, T Sato… - Journal of Leucocyte …, 2004 - academic.oup.com
Tissue accumulation of leukocytes constitutes a rate-limiting step in endotoxin-induced
tissue injury. Chemokines have the capacity to regulate leukocyte trafficking. However, the …

Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and KC

AB Lentsch, H Yoshidome, WG Cheadle, FN Miller… - Hepatology, 1998 - journals.lww.com
Hepatic injury induced by ischemia and reperfusion is an important clinical problem after
liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the …

Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and Kupffer cells

AB Lentsch, H Yoshidome, WG Cheadle, FN Miller… - Hepatology, 1998 - journals.lww.com
Hepatic injury induced by ischemia and reperfusion is an important clinical problem after
liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the …

[HTML][HTML] The chemokine receptor CXCR3 limits injury after acute toxic liver damage

MM Zaldivar, ML Berres, H Sahin, A Nellen… - Laboratory …, 2012 - nature.com
Although acute liver failure is a rare disease, its presence is associated with high morbidity
and mortality in affected patients. While a contribution of the immune system to the outcome …

[PDF][PDF] Hepatocyte signaling through CXC chemokine receptor‐2 is detrimental to liver recovery after ischemia/reperfusion in mice

S Kuboki, T Shin, N Huber, T Eismann, E Galloway… - …, 2008 - Wiley Online Library
CXC chemokines and their receptor, CXC chemokine receptor‐2 (CXCR2), are important
components of the hepatic inflammatory response to ischemia/reperfusion (I/R). However …

Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin toxicity

JC Hanson, MK Bostick, CB Campe, P Kodali, G Lee… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: CXC chemokines function as survival factors for several types of
cells. In this study, we investigated whether CXC chemokines promote survival of liver cells …

Critical role of CXC chemokines in endotoxemic liver injury in mice

H Jaeschke, ML Bajt - Journal of leukocyte biology, 2004 - academic.oup.com
Dear Editor: We read with great interest the recent paper by Li et al.[1], who reported
evidence for a critical role of the CXC chemokines keratinocyte (KC) and macrophage …

Proliferative effects of CXC chemokines in rat hepatocytes in vitro and in vivo

LM Colletti, M Green, MD Burdick, SL Kunkel… - Shock, 1998 - journals.lww.com
The CXC chemokines have well-documented neutrophil chemotactic, angiogenic, and
mitogenic properties. The current investigations evaluate the effects of interleukin-8 (IL-8) …

Cell-specific regulatory effects of CXCR2 on cholestatic liver injury

T Konishi, RM Schuster… - American Journal …, 2019 - journals.physiology.org
The CXC chemokine receptor 2 (CXCR2) is critical for neutrophil recruitment and
hepatocellular viability but has not been studied in the context of cholestatic liver injury …