Importance of radiobiological studies for the advancement of boron neutron capture therapy (BNCT)

AM Hughes - Expert Reviews in Molecular Medicine, 2022 - cambridge.org
Boron neutron capture therapy (BNCT) is a tumour selective particle radiotherapy, based on
the administration of boron carriers incorporated preferentially by tumour cells, followed by …

Optimizing boron neutron capture therapy (BNCT) to treat cancer: an updated review on the latest developments on boron compounds and strategies

A Monti Hughes, N Hu - Cancers, 2023 - mdpi.com
Simple Summary Boron neutron capture therapy (BNCT) is a tumor-selective particle
radiotherapy. It combines preferential boron accumulation in tumors and neutron irradiation …

Initiatives toward clinical boron neutron capture therapy in Japan

A Matsumura, T Asano, K Hirose, H Igaki… - Cancer biotherapy & …, 2023 - liebertpub.com
Boron neutron capture therapy (BNCT) has been performed at nuclear research reactors for
many years. The development of accelerators for BNCT resulted in a paradigm shift from …

A review of planned, ongoing clinical studies and recent development of BNCT in mainland of china

Z Zhang, Y Chong, Y Liu, J Pan, C Huang, Q Sun, Z Liu… - Cancers, 2023 - mdpi.com
Simple Summary Boron neutron capture therapy (BNCT) is an innovative radiation therapy
that shows promise in treating certain types of cancer. Recent advancements in BNCT have …

Boron neutron capture therapy: Moving toward targeted cancer therapy

HR Mirzaei, A Sahebkar, R Salehi… - Journal of cancer …, 2016 - journals.lww.com
Boron neutron capture therapy (BNCT) occurs when a stable isotope, boton-10, is irradiated
with low-energy thermal neutrons to yield stripped down helium-4 nuclei and lithium-7 …

Diagnostic and Theranostic Technologies Used in Boron Neutron Capture Therapy-A Brief Review

P Coghi, T Fazal, NS Hosmane, Y Zhu - Inorganic Chemistry …, 2023 - Elsevier
Boron neutron capture therapy (BNCT) is a highly targeted, selective and effective technique
to cure various types of cancers, with less harms to the healthy cells. In principle, BNCT …

Early clinical trial concept for boron neutron capture therapy: a critical assessment of the EORTC trial 11001

A Wittig, L Collette, R Moss, WA Sauerwein - Applied Radiation and …, 2009 - Elsevier
BNCT causes selective damage to tumor cells by neutron capture reactions releasing high
LET-particles where 10B-atoms are present. Neither the 10B-compound nor thermal …

Present status and perspectives of boron neutron capture therapy

D Gabel - Radiotherapy and Oncology, 1994 - Elsevier
Boron neutron capture therapy (BNCT) is a mode of radiotherapy with great attractiveness,
but also with a burden of past failure. In this review, the principles of BNCT, the reasons for …

A realistic appraisal of boron neutron capture therapy as a cancer treatment modality

RF Barth, Z Zhang, T Liu - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary therapeutic modality based on the nuclear
capture and fission reactions that occur when the stable isotope boron-10 is irradiated with …

Boron neutron capture therapy: Current status and challenges

S Wang, Z Zhang, L Miao, Y Li - Frontiers in Oncology, 2022 - frontiersin.org
Boron neutron capture therapy (BNCT) is a re-emerging therapy with the ability to selectively
kill tumor cells. After the boron delivery agents enter the tumor tissue and enrich the tumor …