Embryo culture at a reduced oxygen concentration of 5%: a mini review
R Sciorio, GD Smith - Zygote, 2019 - cambridge.org
The optimum oxygen tension for culturing mammalian embryos has been widely debated by
the scientific community. While several laboratories have moved to using 5% as the value for …
the scientific community. While several laboratories have moved to using 5% as the value for …
Relationships between energy metabolism and development of early mammalian embryos
D Rieger - Theriogenology, 1992 - Elsevier
Early embryo development requires the production and expenditure of large amounts of
cellular energy for cell growth, division and differentiation. Consequently, information about …
cellular energy for cell growth, division and differentiation. Consequently, information about …
Changes in requirements and utilization of nutrients during mammalian preimplantation embryo development and their significance in embryo culture
DK Gardner - Theriogenology, 1998 - Elsevier
Along with the transition from maternal to embryonic genome control the mammalian
preimplantation embryo undergoes significant changes in its physiology during …
preimplantation embryo undergoes significant changes in its physiology during …
Detection of reactive oxygen species (ROS) and apoptosis in human fragmented embryos.
HW Yang, KJ Hwang, HC Kwon, HS Kim… - Human reproduction …, 1998 - academic.oup.com
In human in-vitro fertilization (IVF)-embryo transfer, the in-vitro culture environment differs
from in-vivo conditions in that the oxygen concentration is higher, and in such conditions the …
from in-vivo conditions in that the oxygen concentration is higher, and in such conditions the …
Oxidative stress on mouse embryo development in vitro
Y Goto, Y Noda, K Narimoto, Y Umaoka… - Free Radical Biology and …, 1992 - Elsevier
Oxygen radicals are involved in the in vitro block phenomenon of embryo development,
because a low oxygen tension and superoxide dismutase (SOD) have been shown to …
because a low oxygen tension and superoxide dismutase (SOD) have been shown to …
The regulation of trophoblast differentiation by oxygen in the first trimester of pregnancy
JL James, PR Stone, LW Chamley - Human reproduction update, 2006 - academic.oup.com
In the first trimester of human pregnancy villous cytotrophoblasts are able to differentiate to
form either the overlying syncytiotrophoblast layer or, in anchoring villi, extravillous …
form either the overlying syncytiotrophoblast layer or, in anchoring villi, extravillous …
Differential sensitivity of male and female mouse embryos to oxidative induced heat‐stress is mediated by glucose‐6‐phosphate dehydrogenase gene expression
M Pérez‐Crespo, MA Ramirez… - Molecular …, 2005 - Wiley Online Library
During the preimplantation period, in vitro cultured males have a higher metabolic rate,
different gene expression, and grow faster than females. It has been suggested that under …
different gene expression, and grow faster than females. It has been suggested that under …
Effect of oxygen concentration and free radicals on in vitro development of in vitro-produced bovine embryos
Y Fujitani, K Kasai, S Ohtani, K Nishimura… - Journal of animal …, 1997 - academic.oup.com
The effects of free radicals and hypotaurine on the development of bovine embryos
produced by in vitro fertilization of in vitro-matured oocytes were examined. Embryos that …
produced by in vitro fertilization of in vitro-matured oocytes were examined. Embryos that …
Quiet please, do not disturb: a hypothesis of embryo metabolism and viability
HJ Leese - Bioessays, 2002 - Wiley Online Library
This review uses nutritional markers of normal and impaired development to address the
question; what makes a viable mammalian preimplantation embryo? Resolution of this …
question; what makes a viable mammalian preimplantation embryo? Resolution of this …
In vitro fertilization (IVF) in mammals: epigenetic and developmental alterations. Scientific and bioethical implications for IVF in humans
P Ventura-Juncá, I Irarrázaval, AJ Rolle, JI Gutiérrez… - Biological Research, 2015 - Springer
The advent of in vitro fertilization (IVF) in animals and humans implies an extraordinary
change in the environment where the beginning of a new organism takes place. In mammals …
change in the environment where the beginning of a new organism takes place. In mammals …