NLRP3 is the best characterized cytosolic nod-like pattern recognition receptor which can
detect microbial motifs, endogenous danger and stress signals. Activation of NLRP3 leads to …

NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) is a cytosolic pattern
recognition receptor (PRR) that recognizes multiple pathogen-associated molecular patterns …

The NLRP3 inflammasome is a cytoplasmic multiprotein complex, the assembly of which
can be initiated in response to various exogenous or endogenous danger signals …

The NLRP3 inflammasome is a multi-protein complex that initiates innate immunity
responses when exposed to a wide range of stimuli, including pathogen-associated …

NLRP3 inflammasome is an intracellular protein complex that initiates cellular injury via
assembly of NLRP3, ASC and caspase-1 in response to microbial infection and sterile …

Inflammasomes are cytosolic pattern recognition receptors that recognize pathogen-
associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs) …

Inflammation is a host protection mechanism that eliminates invasive pathogens from the
body. However, chronic inflammation, which occurs repeatedly and continuously over a long …

The NLRP3 inflammasome is activated in response to a variety of signals that are indicative
of damage to the host including tissue damage, metabolic stress, and infection. Upon …

Inflammation is a protective reaction activated in response to detrimental stimuli, such as
dead cells, irritants or pathogens, by the evolutionarily conserved immune system and is …

The NLRP3 inflammasome is a multimeric protein complex that initiates an inflammatory
form of cell death and triggers the release of proinflammatory cytokines IL-1β and IL-18. The …