Load adaptability in patients with pulmonary arterial hypertension
M Amsallem, D Boulate, M Aymami, J Guihaire… - The American Journal of …, 2017 - Elsevier
Right ventricular (RV) adaptation to pressure overload is a major prognostic factor in
patients with pulmonary arterial hypertension (PAH). The objectives were first to define the …
patients with pulmonary arterial hypertension (PAH). The objectives were first to define the …
Models for pulmonary hypertension
GR Marsboom, SP Janssens - Drug Discovery Today: Disease Models, 2004 - Elsevier
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure (PAP) greater
than 25mmHg at rest or greater than 30mmHg during exercise, eventually leading to right …
than 25mmHg at rest or greater than 30mmHg during exercise, eventually leading to right …
Exercise training and pulmonary arterial hypertension: A review of the cardiac benefits
LL Soares, FR Drummond, VN Lavorato… - Science & Sports, 2018 - Elsevier
Aims Patients of pulmonary arterial hypertension (PAH) exhibit reduced functional capacity
and exercise tolerance. Despite the evidences that exercise training is beneficial to this …
and exercise tolerance. Despite the evidences that exercise training is beneficial to this …
Current pathophysiological concepts and management of pulmonary hypertension
AP Lourenço, D Fontoura, T Henriques-Coelho… - International journal of …, 2012 - Elsevier
Pulmonary hypertension (PH), increasingly recognized as a major health burden, remains
underdiagnosed due mainly to the unspecific symptoms. Pulmonary arterial hypertension …
underdiagnosed due mainly to the unspecific symptoms. Pulmonary arterial hypertension …
Right ventricular remodeling in idiopathic pulmonary arterial hypertension: adaptive versus maladaptive morphology
R Badagliacca, R Poscia, B Pezzuto, M Nocioni… - The Journal of Heart and …, 2015 - Elsevier
Background Although increased pulmonary pressure is caused by changes in the
pulmonary vasculature, prognosis in idiopathic pulmonary arterial hypertension (IPAH) is …
pulmonary vasculature, prognosis in idiopathic pulmonary arterial hypertension (IPAH) is …
The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension
HJ Bogaard, K Abe, AV Noordegraaf, NF Voelkel - Chest, 2009 - Elsevier
Pulmonary arterial hypertension (PAH) is a deadly disease in which vasoconstriction and
vascular remodeling both lead to a progressive increase in pulmonary vascular resistance …
vascular remodeling both lead to a progressive increase in pulmonary vascular resistance …
Novel assessment of haemodynamic kinetics with acute exercise in a rat model of pulmonary arterial hypertension
MB Brown, TJ Chingombe, AB Zinn… - Experimental …, 2015 - Wiley Online Library
New Findings What is the central question of this study? The acute effect of exercise at
moderately high intensity on already‐elevated pulmonary arterial pressures and right …
moderately high intensity on already‐elevated pulmonary arterial pressures and right …
Understanding right and left ventricular systolic function and interactions at rest and with exercise in primary pulmonary hypertension
M Nootens, CJ Wolfkiel, EV Chomka, S Rich - The American journal of …, 1995 - Elsevier
The effort limitation in primary pulmonary hypertension (PPH) is thought to result from an
inability to increase cardiac output with exercise. The precise mechanism, however, is …
inability to increase cardiac output with exercise. The precise mechanism, however, is …
Ventricular interdependence in pulmonary arterial hypertension: providing small pieces of a complex puzzle.
TM Gorter, TP Willems, JP van Melle - European Journal of Heart …, 2015 - europepmc.org
Ventricular interdependence in pulmonary arterial hypertension: providing small pieces of a
complex puzzle. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …
complex puzzle. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …
Quadriceps muscle fibre dysfunction in patients with pulmonary arterial hypertension
E Manders, G Ruiter, HJ Bogaard… - European …, 2015 - Eur Respiratory Soc
Despite improvements in disease targeted therapies, pulmonary arterial hypertension (PAH)
is a progressive disease and PAH patients remain symptomatic [1]. Exercise intolerance is …
is a progressive disease and PAH patients remain symptomatic [1]. Exercise intolerance is …