[HTML][HTML] Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk
AB Goldfine, SE Shoelson - The Journal of clinical …, 2017 - Am Soc Clin Investig
Obesity-related sub-acute chronic inflammation has been associated with incident type 2
diabetes and atherosclerotic cardiovascular disease. Inflammation is increasingly …
diabetes and atherosclerotic cardiovascular disease. Inflammation is increasingly …
Therapeutic approaches to target inflammation in type 2 diabetes
AB Goldfine, V Fonseca, SE Shoelson - Clinical chemistry, 2011 - academic.oup.com
BACKGROUND Chronic inflammation may participate in the pathogenesis of insulin
resistance, type 2 diabetes, and cardiovascular disease and may be a common denominator …
resistance, type 2 diabetes, and cardiovascular disease and may be a common denominator …
[HTML][HTML] Inflammation in the pathogenesis of microvascular complications in diabetes
DV Nguyen, LC Shaw, MB Grant - Frontiers in endocrinology, 2012 - frontiersin.org
Diabetes and hyperglycemia create a proinflammatory microenvironment that progresses to
microvascular complications such as nephropathy, retinopathy, and neuropathy. Diet …
microvascular complications such as nephropathy, retinopathy, and neuropathy. Diet …
[HTML][HTML] The role of inflammation in diabetes: current concepts and future perspectives
S Tsalamandris, AS Antonopoulos… - European cardiology …, 2019 - ncbi.nlm.nih.gov
Diabetes is a complex metabolic disorder affecting the glucose status of the human body.
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …
[HTML][HTML] Thrombosis and vascular inflammation in diabetes: mechanisms and potential therapeutic targets
N Pechlivani, RA Ajjan - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Cardiovascular disease remains the main cause of morbidity and mortality in patients with
diabetes. The risk of vascular ischemia is increased in this population and outcome …
diabetes. The risk of vascular ischemia is increased in this population and outcome …
Type 2 diabetes as an inflammatory cardiovascular disorder
D Ziegler - Current molecular medicine, 2005 - ingentaconnect.com
Type 2 diabetes carries a 2-6-fold increased risk of cardiovascular disease (CVD) and
death. Indeed, the risk of major cardiovascular events in Type 2 diabetic patients without …
death. Indeed, the risk of major cardiovascular events in Type 2 diabetic patients without …
Diabetes mellitus and inflammation
E Lontchi-Yimagou, E Sobngwi, TE Matsha… - Current diabetes …, 2013 - Springer
Type 2 diabetes mellitus (T2DM) is increasingly common worldwide. Related complications
account for increased morbidity and mortality, and enormous healthcare spending …
account for increased morbidity and mortality, and enormous healthcare spending …
Metabolic syndrome, insulin resistance, and roles of inflammation–mechanisms and therapeutic targets
GR Romeo, J Lee, SE Shoelson - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
Obesity and its comorbidities, including type 2 diabetes mellitus and cardiovascular disease,
are associated with a state of chronic low-grade inflammation that can be detected both …
are associated with a state of chronic low-grade inflammation that can be detected both …
Obesity and metabolic inflammation
H Xu - Drug Discovery Today: Disease Mechanisms, 2013 - Elsevier
Obesity epidemics affect 35.7% of adults and approximately 17% of children in the United
States. Obesity has been associated with several health disorders such as type 2 diabetes …
States. Obesity has been associated with several health disorders such as type 2 diabetes …
[PDF][PDF] Inflammation in obesity, diabetes, and related disorders
Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …