Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications …

ST McSorley, RD Dolan, CSD Roxburgh… - European Journal of …, 2019 - Elsevier
Background Perioperative dexamethasone is associated with attenuation of the
postoperative systemic inflammatory response and fewer postoperative complications …

The impact of preoperative dexamethasone on the magnitude of the postoperative systemic inflammatory response and complications following surgery for colorectal …

ST McSorley, CSD Roxburgh, PG Horgan… - Annals of surgical …, 2017 - Springer
Background The magnitude of the postoperative systemic inflammatory response (SIR), as
evidenced by C-reactive protein (CRP), is associated with both short-and long-term …

Does single, low-dose preoperative dexamethasone improve outcomes after colorectal surgery based on an enhanced recovery protocol? Double-blind, randomized …

T Kirdak, A Yilmazlar, S Cavun, I Ercan… - The American …, 2008 - journals.sagepub.com
Preoperative single, high-dose methylprednisolone administration improves postoperative
outcomes after colonic surgery. Several randomized studies, including major surgeries …

Perioperative intravenous dexamethasone for patients undergoing colorectal surgery: a systematic review and meta-analysis

T McKechnie, G Elder, S Ichhpuniani, AT Chen… - International Journal of …, 2023 - Springer
Purpose Dexamethasone is a glucocorticoid that is often administered intraoperatively as
prophylaxis for postoperative nausea and vomiting (PONV). Several randomized controlled …

Association between intraoperative dexamethasone and postoperative mortality in patients undergoing oncologic surgery: a multicentric cohort study

M Blank, A Katsiampoura, LJ Wachtendorf… - Annals of …, 2023 - journals.lww.com
Objective: We examined the effects of dexamethasone on postoperative mortality,
recurrence-free survival, and side effects in patients undergoing oncologic operations …

Association between preoperative glucocorticoids and long-term survival and cancer recurrence after colectomy: follow-up analysis of a previous randomized …

PP Singh, DP Lemanu, MHG Taylor… - British Journal of …, 2014 - academic.oup.com
Background The effect of anaesthetic drugs on long-term oncological outcomes after cancer
surgery is an area of current interest. Dexamethasone is widely used in anaesthetic practice; …

Avoiding perioperative dexamethasone may improve the outcome of patients with rectal cancer

HC Yu, YX Luo, H Peng, L Kang, MJ Huang… - European Journal of …, 2015 - Elsevier
Background Perioperative administration of dexamethasone may augment recurrence and
mortality after tumor resection possibly by immunosuppression, which, unfortunately, has …

Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial)

DREAMS Trial Collaborators… - bmj, 2017 - bmj.com
Objectives To determine whether preoperative dexamethasone reduces postoperative
vomiting in patients undergoing elective bowel surgery and whether it is associated with …

Effect of prednisolone on local and systemic response in laparoscopic vs. open colon surgery: a randomized, double-blind, placebo-controlled trial

A Vignali, S Di Palo, E Orsenigo… - Diseases of the colon …, 2009 - journals.lww.com
PURPOSE: This study was designed to assess whether preoperative, short-term,
intravenously administered high doses of methylprednisolone (30 mg/kg 90 minutes before …

Randomized controlled trial: perioperative dexamethasone reduces excessive postoperative inflammatory response and ileus after surgery for inflammatory bowel …

T Zhang, Y Xu, Y Yao, L Jin, H Liu… - Inflammatory Bowel …, 2021 - academic.oup.com
Background An excessive postoperative inflammatory response is common after surgery for
inflammatory bowel disease (IBD) and may be associated with an increased incidence of …