The evolution of therapies in non-small cell lung cancer
V Boolell, M Alamgeer, DN Watkins, V Ganju - Cancers, 2015 - mdpi.com
The landscape of advanced non-small lung cancer (NSCLC) therapies has rapidly been
evolving beyond chemotherapy over the last few years. The discovery of oncogenic driver …
evolving beyond chemotherapy over the last few years. The discovery of oncogenic driver …
Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy
M Saito, H Suzuki, K Kono, S Takenoshita, T Kohno - Surgery today, 2018 - Springer
Lung adenocarcinoma (LADC) is a cancer treatable using targeted therapies against driver
gene aberrations. EGFR mutations and ALK fusions are frequent gene aberrations in LADC …
gene aberrations. EGFR mutations and ALK fusions are frequent gene aberrations in LADC …
TP53, STK11, and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti–PD-1 in Lung Adenocarcinoma
J Biton, A Mansuet-Lupo, N Pécuchet, M Alifano… - Clinical Cancer …, 2018 - AACR
Purpose: By unlocking antitumor immunity, antibodies targeting programmed cell death 1
(PD-1) exhibit impressive clinical results in non–small cell lung cancer, underlining the …
(PD-1) exhibit impressive clinical results in non–small cell lung cancer, underlining the …
[HTML][HTML] AKT-STAT3 pathway as a downstream target of EGFR signaling to regulate PD-L1 expression on NSCLC cells
S Abdelhamed, K Ogura, S Yokoyama, I Saiki… - Journal of …, 2016 - ncbi.nlm.nih.gov
While cancer development and progression can be controlled by cytotoxic T cells, it is also
known that tumor-specific CD8+ T cells become functionally impaired by acquiring a group …
known that tumor-specific CD8+ T cells become functionally impaired by acquiring a group …
Biomarker-targeted therapies in non–small cell lung cancer: current status and perspectives
H Guo, J Zhang, C Qin, H Yan, T Liu, H Hu, S Tang… - Cells, 2022 - mdpi.com
Non-small-cell lung cancer (NSCLC) is one of the most common malignancies and the
leading causes of cancer-related death worldwide. Despite many therapeutic advances in …
leading causes of cancer-related death worldwide. Despite many therapeutic advances in …
Cytokine profile in lung cancer patients: anti-tumor and oncogenic cytokines
FE Essogmo, AV Zhilenkova, YSN Tchawe… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is currently the second leading cause of cancer death
worldwide. Cytokines are small proteins that carry messages between cells and are known …
worldwide. Cytokines are small proteins that carry messages between cells and are known …
[HTML][HTML] The emerging treatment landscape of advanced non-small cell lung cancer
P Economopoulou, G Mountzios - Annals of Translational Medicine, 2018 - ncbi.nlm.nih.gov
Lung cancer remains the leading cause of cancer related death worldwide. Despite broad
advances in diagnostics and therapy, the five-year overall survival for patients with …
advances in diagnostics and therapy, the five-year overall survival for patients with …
Targeted therapy for non-small-cell lung cancer: past, present and future
PM Forde, DS Ettinger - Expert review of anticancer therapy, 2013 - Taylor & Francis
Therapy for advanced non-small-cell lung cancer has developed significantly with new
awareness of histologic subtype as an important factor in guiding treatment and the …
awareness of histologic subtype as an important factor in guiding treatment and the …
Targeting the PI3K/Akt/mTOR pathway in non‐small cell lung cancer (NSCLC)
AC Tan - Thoracic cancer, 2020 - Wiley Online Library
The traditional classification of lung cancer into small cell lung cancer and non‐small cell
lung cancer (NSCLC) has been transformed with the increased understanding of the …
lung cancer (NSCLC) has been transformed with the increased understanding of the …
Next generation sequencing and genetic alterations in squamous cell lung carcinoma: where are we today?
Lung cancer is the leading cause of cancer-related mortality and will affect~ 6% of the
population. It is divided into two broad categories, small cell lung cancer and non-small cell …
population. It is divided into two broad categories, small cell lung cancer and non-small cell …