Functional implications of microRNAs in Crohn's disease revealed by integrating microRNA and messenger RNA expression profiling

O Palmieri, TM Creanza, F Bossa, T Latiano… - International journal of …, 2017 - mdpi.com
Crohn's disease (CD) is a debilitating inflammatory bowel disease (IBD) that emerges due to
the influence of genetic and environmental factors. microRNAs (miRNAs) have been …

Serum MicroRNA signature as a diagnostic and therapeutic marker in patients with psoriatic arthritis

SM Wade, T McGarry, SC Wade, U Fearon… - The Journal of …, 2020 - jrheum.org
Objective MicroRNA (miRNA) are small endogenous regulatory RNA molecules that have
emerged as potential therapeutic targets and biomarkers in autoimmunity. Here, we …

Circulating microRNAs as candidate biomarkers in patients with systemic lupus erythematosus

H Wang, W Peng, X Ouyang, W Li, Y Dai - Translational Research, 2012 - Elsevier
Aberrant expression of microRNAs (miRNAs) has been identified in various diseases.
Recent studies demonstrated that miRNAs can be detected in the circulation and serve as …

Intestinal and circulating microRNAs in coeliac disease

C Felli, A Baldassarre, A Masotti - International journal of molecular …, 2017 - mdpi.com
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at the post-
transcriptional level and play a key role in the pathogenesis of autoimmune and …

MicroRNA signatures differentiate Crohn's disease from ulcerative colitis

JS Schaefer, T Attumi, AR Opekun, B Abraham, J Hou… - BMC immunology, 2015 - Springer
Background Excessive and inappropriate immune responses are the hallmark of several
autoimmune disorders, including the inflammatory bowel diseases (IBD): Crohn's disease …

Peripheral blood mononuclear cell microRNAs are novel biomarkers for diagnosing and monitoring Crohn's disease

H Chen, P Li, J Chen, Y Wang, Q Yu, Y Wu… - The FASEB …, 2022 - Wiley Online Library
Crohn's disease is a recurrent, progressive, immune‐mediated inflammatory disease and
merely manifests non‐specific symptoms at early stage. In this study, we isolated peripheral …

Clinical significance of miRNAs in autoimmunity

L Zhang, H Wu, M Zhao, C Chang, Q Lu - Journal of autoimmunity, 2020 - Elsevier
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …

Inflammation-related differentially expressed common miRNAs in systemic autoinflammatory disorders patients can regulate the clinical course.

TH Akbaba, YZ Akkaya-Ulum… - Clinical and …, 2021 - europepmc.org
Objectives Systemic autoinflammatory diseases (SAIDs) are caused by the malfunctioning of
the innate immune system factors. Clinical heterogeneity and undefined pathobiology are …

MicroRNAs as biomarkers in rheumatic diseases

I Alevizos, GG Illei - Nature Reviews Rheumatology, 2010 - nature.com
MicroRNAs (miRNAs) are endogenous, noncoding, single-stranded RNAs of 19–25
nucleotides in length. They regulate gene expression and are important in a wide range of …

Plasma microRNA profile differentiates Crohn's colitis from ulcerative colitis

U Netz, J Carter, MR Eichenberger… - Inflammatory bowel …, 2018 - academic.oup.com
Background Inflammatory bowel disease (IBD) is commonly divided into 2 entities: Crohn's
disease (CD) and ulcerative colitis (UC). Differentiating between these entities when dealing …