[HTML][HTML] A dramatic rise in serum ACE2 activity in a critically ill COVID-19 patient

B Nagy Jr, Z Fejes, Z Szentkereszty, R Sütő… - International Journal of …, 2021 - Elsevier
Endothelial cells express surface angiotensin-converting enzyme 2 (ACE2), the main
receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that promotes …

[HTML][HTML] Circulating ACE2 activity predicts mortality and disease severity in hospitalized COVID-19 patients

M Fagyas, Z Fejes, R Sütő, Z Nagy, B Székely… - International Journal of …, 2022 - Elsevier
Objectives Angiotensin-converting enzyme 2 (ACE2) represents the primary receptor for
SARS-CoV-2 to enter endothelial cells. Here we investigated circulating ACE2 activity to …

COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

S Beyerstedt, EB Casaro, ÉB Rangel - European journal of clinical …, 2021 - Springer
COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

SK Patel, JA Juno, WS Lee, KM Wragg… - European …, 2021 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) causes persistent endothelial inflammation, lung,
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …

Expression of ACE2, soluble ACE2, angiotensin I, angiotensin II and angiotensin-(1-7) is modulated in COVID-19 patients

IO Osman, C Melenotte, P Brouqui, M Million… - Frontiers in …, 2021 - frontiersin.org
The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …

[HTML][HTML] A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells

Y Wang, Y Wang, W Luo, L Huang, J Xiao… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
The outbreak of pneumonia caused by SARS-CoV-2 posed a great threat to global human
health, which urgently requires us to understand comprehensively the mechanism of SARS …

ACE2 protein expression in lung tissues of severe COVID-19 infection

A Gheware, A Ray, D Rana, P Bajpai, A Nambirajan… - Scientific reports, 2022 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells …

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

The Impact of Angiotensin-Converting Enzyme 2 (ACE2) Expression Levels in Patients with Comorbidities on COVID-19 Severity: A Comprehensive Review

R Rodrigues, S Costa de Oliveira - Microorganisms, 2021 - mdpi.com
Angiotensin-Converting Enzyme 2 (ACE2) has been proved to be the main host cell receptor
for the binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the …

Soluble angiotensin‐converting enzyme 2 is transiently elevated in COVID‐19 and correlates with specific inflammatory and endothelial markers

A Lundström, L Ziegler, S Havervall… - Journal of Medical …, 2021 - Wiley Online Library
The main entry receptor of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
is angiotensin‐converting enzyme 2 (ACE2). SARS‐CoV‐2 interactions with ACE2 may …