The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary
thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced …

SLC5A8, proposed as a thyroid apical iodide transporter, was recently defined as a Na+-
coupled transporter of short-chain fatty acid. To document the expression pattern of SLC5A8 …

Cancer arises through accumulation of epigenetic and genetic alteration. Aberrant promoter
methylation is a common epigenetic mechanism of gene silencing in cancer cells. We here …

Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a
recent increase in incidence in many countries. Although PTC has been explored by gene …

The BRAF V600E mutation plays an important role in the tumorigenesis of papillary thyroid
cancer (PTC). To explore an epigenetic mechanism involved in this process, we performed a …

Context: Aberrant DNA methylation is known to be a major factor in oncogenesis and cancer
progression, but effects of methylation in papillary thyroid cancer (PTC) are not well defined …

Aberrant gene methylation plays an important role in human tumorigenesis, including
thyroid tumorigenesis. Many tumor suppressor genes are aberrantly methylated in thyroid …

Our aim was to comprehensively analyze promoter hypermethylation of a panel of novel and
known methylation markers for thyroid neoplasms and to establish their relationship with …

Thyroid cancer is a heterogeneous disease with several subtypes characterized by
cytological, histological and genetic alterations, but the involvement of epigenetics is not …

Objective: The purpose of this study was to determine the global patterns of aberrant DNA
methylation in thyroid cancer. Research Design and Methods: We have used DNA …