Creation and phenotypic analysis of alpha-lactalbumin-deficient mice.
MG Stinnakre, JL Vilotte, S Soulier… - Proceedings of the …, 1994 - National Acad Sciences
alpha-Lactalbumin is an abundant milk-specific calcium metalloprotein which has an
evolutionary relationship to lysozyme. It modifies the substrate specificity of a Golgi …
evolutionary relationship to lysozyme. It modifies the substrate specificity of a Golgi …
Lactation is disrupted by alpha-lactalbumin deficiency and can be restored by human alpha-lactalbumin gene replacement in mice.
A Stacey, A Schnieke, M Kerr, A Scott… - Proceedings of the …, 1995 - National Acad Sciences
Mice carrying either a deletion of the murine alpha-lactalbumin (alpha-lac) gene (null allele)
or its replacement by the human alpha-lac gene (humanized allele) have been generated by …
or its replacement by the human alpha-lac gene (humanized allele) have been generated by …
α-Lactalbumin
K Brew - Advanced Dairy Chemistry—1 Proteins: Part A/Part B, 2003 - Springer
Abstract α-Lactalbumin (α-La) is a unique protein component of milk whey in all mammalian
subdivisions, the eutherians, marsupials and monotremes. Following its early isolation by …
subdivisions, the eutherians, marsupials and monotremes. Following its early isolation by …
Isolation and characterization of the mouse α-lactalbumin-encoding gene: interspecies comparison, tissue-and stage-specific expression
JL Vilotte, S Soulier - Gene, 1992 - Elsevier
The murine α-lactalbumin-encoding gene (mαLa) was isolated and completely sequenced.
The 2.3-kb transcription unit shared a similar organization with that of its counterparts from …
The 2.3-kb transcription unit shared a similar organization with that of its counterparts from …
Molecular cloning and nucleotide sequence of a bovine α-lactalbumin cDNA
WL Hurley, LA Schuler - Gene, 1987 - Elsevier
A cDNA clone for the bovine milk protein, α-lactalbumin (αLA), has been identified using a
rat cDNA probe. The bovine cDNA clone is 703 nucleotides (nt) long, contains 8 nt of 5' …
rat cDNA probe. The bovine cDNA clone is 703 nucleotides (nt) long, contains 8 nt of 5' …
effects of increased expression of α-lactalbumin in transgenic mice on milk yield and pup growth
WS Boston, GT Bleck, JC Conroy, MB Wheeler… - Journal of dairy …, 2001 - Elsevier
Lactose synthase (a complex of β1, 4-galactosyltransferase and α-lactalbumin) forms
lactose in the Golgi complex of mammary epithelial cells. To determine whether α …
lactose in the Golgi complex of mammary epithelial cells. To determine whether α …
[HTML][HTML] Expression and characterization of bioactive recombinant human α-lactalbumin in the milk of transgenic cloned cows
J Wang, P Yang, B Tang, X Sun, R Zhang, C Guo… - Journal of dairy …, 2008 - Elsevier
Improvement of the nutritional value of cow milk with transgenic expression of recombinant
human α-lactalbumin (α-LA) has been previously attempted. However, the detailed …
human α-lactalbumin (α-LA) has been previously attempted. However, the detailed …
Biological role of α-lactalbumin: a review
KE Ebner, U Brodbeck - Journal of Dairy Science, 1968 - Elsevier
The biological role of α-lactalbumin has been elucidated recently. It is one of two proteins
required for the lactose synthetase enzyme, the enzyme responsible for the biosynthesis of …
required for the lactose synthetase enzyme, the enzyme responsible for the biosynthesis of …
α-Lactalbumin and the origins of lactation
V Hayssen, DG Blackburn - Evolution, 1985 - JSTOR
1148 NOTES AND COMMENTS portant to offspring survival in all oviparous vertebrates
(Board and Fuller, 1974). Specializations for protection of the eggs from microbial attack are …
(Board and Fuller, 1974). Specializations for protection of the eggs from microbial attack are …
Nutritional and physiologic significance of α-lactalbumin in infants
B Lönnerdal, EL Lien - Nutrition Reviews, 2003 - academic.oup.com
Abstract α-Lactalbumin is the major protein in breast milk (20-25% of total protein) and has
been described to have several physiologic functions in the neonatal period. In the …
been described to have several physiologic functions in the neonatal period. In the …
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