DNA methylation (DNAm) is an epigenetic mark that regulates genome function and is
important for normal development in mammals. To understand the complex interplay …

Methylation is an important epigenetic regulation of methylation genes that plays a crucial
role in regulating biological processes. While traditional methods for detecting methylation in …

Gene expression influences various physiological functions and plays a critical role in
disease progression. One of the key mechanisms governing gene expression is DNA …

The next generation sequencing technologies have enabled DNA methylation levels to be
assayed at single-base resolution in the whole genome, but this method is relatively …

Background DNA methylation (DNAm) is an epigenetic regulator of gene expression
programs that can be altered by environmental exposures, aging, and in pathogenesis …

Introduction: DNA methylation is a critical epigenetic modification involving the addition of a
methyl group to the DNA molecule, playing a key role in regulating gene expression without …

Motivation DNA methylation plays an important role in epigenetic modification, the
occurrence, and the development of diseases. Therefore, identification of DNA methylation …

Precision medicine relies on the identification of robust disease and risk factor signatures
from omics data. However, current knowledge-driven approaches may overlook novel or …

DNA methylation plays a crucial role in the establishment of tissue-specific gene expression
and the regulation of key biological processes. However, our present inability to predict the …

DNA methylation plays a crucial role in establishing tissue-specific gene expression.
However, our incomplete understanding of the cis elements that regulate DNA methylation …