[HTML][HTML] Statin therapy in very old patients: lights and shadows

L Cobos-Palacios, J Sanz-Cánovas… - Frontiers in …, 2021 - frontiersin.org
Atherosclerotic cardiovascular diseases (ASCVD) are the leading cause of death worldwide.
High levels of total cholesterol—and of low-density lipoprotein cholesterol in particular—are …

Efficacy of statin treatment based on cardiovascular outcomes in elderly patients: a standard meta-analysis and Bayesian network analysis

C Zhai, K Hou, R Li, YC Hu, JX Zhang… - Journal of …, 2020 - journals.sagepub.com
Objective Statins have been shown to be beneficial for the prevention of cardiovascular
events. In elderly individuals, the efficacy of statins remains controversial and the …

Real-life benefits of statins for cardiovascular prevention in elderly subjects: a population-based cohort study

J Bezin, N Moore, Y Mansiaux, PG Steg… - The American Journal of …, 2019 - Elsevier
Objectives The benefits of initiating statins in the elderly remains debated. We evaluated the
effects of initiating statins in the elderly, according to cardiovascular risk. Methods This …

Primary prevention of cardiovascular disease with statins in the elderly

Ž Reiner - Current atherosclerosis reports, 2014 - Springer
Owing to the progressive aging of the population, and the fact that cardiovascular disease
(CVD) is the leading cause of death among the elderly, the prevention of CVD in the elderly …

[HTML][HTML] Association of statin use in older people primary prevention group with risk of cardiovascular events and mortality: a systematic review and meta-analysis of …

K Awad, M Mohammed, MM Zaki, AI Abushouk… - BMC medicine, 2021 - Springer
Background Current evidence from randomized controlled trials on statins for primary
prevention of cardiovascular disease (CVD) in older people, especially those aged> 75 …

Drug insight: statin use in the elderly

OC Raffel, HD White - Nature Clinical Practice Cardiovascular Medicine, 2006 - nature.com
The elderly represent a notable proportion of patients who present with myocardial infarction
or acute coronary syndromes. This subgroup of patients also experiences a higher …

[HTML][HTML] Role of statin therapy in primary prevention of cardiovascular disease in elderly patients

TE Strandberg - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review Hypercholesterolemia and statin treatment are nowadays
common among people older than 75 years, but clinical heterogeneity in this increasing age …

Effectiveness of statins for the primary prevention of cardiovascular disease in the Asian elderly population

YW Lin, CC Wang, CC Wu, YT Hsu, FJ Lin - International Journal of …, 2023 - Elsevier
Background Population aging is a global trend, and the elderly have a higher risk of
atherosclerotic cardiovascular disease (ASCVD) and related mortality. Statins have been …

Initiation of statin therapy: are there age limits?

DA Desai, S Zakaria, P Ouyang - Current atherosclerosis reports, 2012 - Springer
Cardiovascular disease (CVD) is the leading cause of death, with a higher prevalence in
older adults who form an increasing proportion of the population of the United States. Statin …

Prescribing statins for cardiovascular disease prevention in the old: an absence of evidence and an absence of guidelines

S Noaman, JE Ibrahim, R Grenfell - Heart, Lung and Circulation, 2014 - Elsevier
Australia's oldest old are potentially being harmed by the under-and over-use of statins.
Variations in prescription of statins are in part due to the vacuum of clinical research trial …