Management of hyperlipidemia in older adults

KP Alexander, MA Blazing… - Journal of …, 2009 - journals.sagepub.com
Cardiovascular disease is the leading cause of death in men and women older than 65
years; therefore, its prevention is an important public health priority. Although cardiovascular …

Safety and effectiveness of statins for prevention of recurrent myocardial infarction in 12 156 typical older patients: a quasi-experimental study

A Ble, PM Hughes, J Delgado, JA Masoli… - … Series A: Biomedical …, 2017 - academic.oup.com
Background: There is limited evidence on statin risk and effectiveness for patients aged 80+.
We estimated risk of recurrent myocardial infarction, muscle-related and other adverse …

Appropriateness of statins in patients aged≥ 80 years and comparison to other age groups

NP Chokshi, FH Messerli, D Sutin… - The American journal of …, 2012 - Elsevier
In patients aged≥ 80 years without previous coronary artery disease, peripheral vascular
disease, or cerebrovascular disease, no evidence has shown a benefit from statin therapy …

Statin use and adverse effects among adults> 75 years of age: insights from the patient and provider assessment of lipid management (PALM) registry

MG Nanna, AM Navar, TY Wang, X Mi… - Journal of the …, 2018 - Am Heart Assoc
Background Current statin use and symptoms among older adults in routine community
practice have not been well characterized since the release of the 2013 American College of …

Long-term cost-effectiveness of statin treatment for primary prevention of cardiovascular disease in the elderly

L Lin, M Teng, YJ Zhao, AL Khoo, RCS Seet… - … drugs and therapy, 2015 - Springer
Purpose This study aimed to evaluate the cost-effectiveness of statins for primary prevention
of stroke and myocardial infarction (MI) in the elderly in Singapore. Methods A Markov model …

Lipid lowering for secondary prevention of cardiovascular disease in older adults

JE Thomas, AM Tershakovec, C Jones-Burton… - Drugs & aging, 2010 - Springer
A perceived lack of evidence for benefit and safety concerns may lead to underprescription
of HMG-CoA reductase inhibitors (statins) in older adults. This article reviews clinical data …

Primary prevention of cardiovascular disease in older adults

AR Barry, DE O'Neill, MM Graham - Canadian Journal of Cardiology, 2016 - Elsevier
Primary prevention of cardiovascular events in older adults is challenging because of a
general paucity of evidence for safe and efficacious therapy. Furthermore, there is no …

How common is statin use in the oldest old?

W Thompson, A Pottegård, JB Nielsen, P Haastrup… - Drugs & Aging, 2018 - Springer
There is a lack of evidence surrounding the efficacy of statins in the oldest old (≥ 80 years of
age). As such, there is controversy surrounding use of statins in this population. We sought …

Statin use and lipid levels in older adults: National Health and Nutrition Examination Survey, 2001 to 2006

JG Robinson, B Booth - Journal of clinical lipidology, 2010 - Elsevier
BACKGROUND: Statins are the evidence-based drugs of choice for the prevention of
cardiovascular disease (CVD). OBJECTIVE: Statin use has increased in those≥ 65 years …

Evaluation and treatment of older patients with hypercholesterolemia: a clinical review

TE Strandberg, L Kolehmainen, A Vuorio - Jama, 2014 - jamanetwork.com
Importance Hypercholesterolemia is common among people older than 80 years.
Substantial functional heterogeneity exists among older patients, and decision making for …