Update on antifungal drug resistance

DS Perlin, E Shor, Y Zhao - Current clinical microbiology reports, 2015 - Springer
Invasive fungal infections remain a major source of global morbidity and mortality, especially
among patients with underlying immune suppression. Successful patient management …

Mechanisms of antifungal drug resistance

LE Cowen, D Sanglard… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

Emerging issues in antifungal resistance

JR Perfect, M Ghannoum - Infectious Disease Clinics, 2020 - id.theclinics.com
This review attempts to frame the issues around antifungal drug resistance. From its
epidemiology, mechanisms, measurements, and clinical significance, invasive fungal …

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …

TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

Antifungal drug resistance: evolution, mechanisms and impact

NM Revie, KR Iyer, N Robbins, LE Cowen - Current opinion in …, 2018 - Elsevier
Highlights•Our limited arsenal of antifungals is threatened by drug-resistant fungal
pathogens.•Inherent resistance is when all strains of a species show antifungal …

Antifungal drug resistance: do molecular methods provide a way forward?

DS Perlin - Current Opinion in Infectious Diseases, 2009 - journals.lww.com
Antifungal drug resistance: do molecular methods provide a w... : Current Opinion in Infectious
Diseases Antifungal drug resistance: do molecular methods provide a way forward? : Current …

Fungal drug response and antimicrobial resistance

P Osset-Trénor, A Pascual-Ahuir, M Proft - Journal of Fungi, 2023 - mdpi.com
Antifungal resistance is a growing concern as it poses a significant threat to public health.
Fungal infections are a significant cause of morbidity and mortality, especially in …

Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Defining the frontiers between antifungal resistance, tolerance and the concept of persistence

E Delarze, D Sanglard - Drug Resistance Updates, 2015 - Elsevier
A restricted number of antifungal agents are available for the therapy of fungal diseases.
With the introduction of epidemiological cut-off values for each agent in important fungal …

Potential strategies to control the risk of antifungal resistance in humans: A comprehensive review

AA Rabaan, T Sulaiman, SH Al-Ahmed, ZA Buhaliqah… - Antibiotics, 2023 - mdpi.com
Fungal infections are becoming one of the main causes of morbidity and mortality in people
with weakened immune systems. Mycoses are becoming more common, despite greater …