[HTML][HTML] Impact of different consensus definition criteria on sepsis diagnosis in a cohort of critically ill patients—insights from a new mathematical probabilistic …

FS Centner, JJ Schoettler, AM Fairley, HA Lindner… - PLoS …, 2020 - journals.plos.org
Background Sepsis-3 definition uses SOFA score to discriminate sepsis from uncomplicated
infection, replacing SIRS criteria that were criticized for being inaccurate. Eligibility of sepsis …

[HTML][HTML] Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy

A Perner, AC Gordon, D De Backer, G Dimopoulos… - Intensive care …, 2016 - Springer
Sepsis is a major growing global burden and a major challenge to intensive care clinicians,
researchers, guideline committee members and policy makers, because of its high and …

[HTML][HTML] Novel evidence on sepsis-inducing pathogens: from laboratory to bedside

S Gatica, B Fuentes, E Rivera-Asín… - Frontiers in …, 2023 - frontiersin.org
Sepsis is a life-threatening condition and a significant cause of preventable morbidity and
mortality globally. Among the leading causative agents of sepsis are bacterial pathogens …

[HTML][HTML] Sepsis biomarkers: past, present and future

G Lippi - Clinical Chemistry and Laboratory Medicine (CCLM), 2019 - degruyter.com
According to the Third International Consensus Definitions for Sepsis and Septic Shock [1],
sepsis is currently defined as severe organ dysfunction caused by a dysregulated host …

Comparison of length of stay and outcomes of patients with positive versus negative blood culture results

D Armstrong-Briley, NST Hozhabri… - Baylor University …, 2015 - Taylor & Francis
In the United States, sepsis is the leading cause of death in critically ill patients. The fatality
rate for severe sepsis is about 40%, and treatment costs over $16 billion annually. It is …

[HTML][HTML] Effect of β-blockers on mortality in patients with sepsis: A propensity-score matched analysis

CL Ge, LN Zhang, YH Ai, W Chen, ZW Ye… - Frontiers in Cellular …, 2023 - frontiersin.org
Objectives We aimed to evaluate the association between β-blocker therapy and mortality in
patients with sepsis. Methods Patients with sepsis were selected from the Medical …

Sepsis subclasses: a framework for development and interpretation

KM DeMerle, DC Angus, JK Baillie, E Brant… - Critical care …, 2021 - journals.lww.com
Sepsis is defined as a dysregulated host response to infection that leads to life-threatening
acute organ dysfunction. It afflicts approximately 50 million people worldwide annually and …

[HTML][HTML] Epidemiologic trends of sepsis in western countries

AS De La Rica, F Gilsanz, E Maseda - Annals of translational …, 2016 - ncbi.nlm.nih.gov
Abstract Since the American College of Chest Physicians (ACCP) and the Society of Critical
care Medicine (SCCM) published the first consensus definition of syndromes related to …

[HTML][HTML] The prevalence, risk factors, and outcomes of sepsis in critically ill patients in China: a multicenter prospective cohort study

M Wang, L Jiang, B Zhu, W Li, B Du, Y Kang… - Frontiers in …, 2020 - frontiersin.org
Background: Sepsis is a main cause of morbidity and mortality in critically ill patients. The
epidemiology of sepsis in high-income countries is well-known, but information on sepsis in …

[HTML][HTML] Methods for phenotyping adult patients in sepsis and septic shock: A scoping review

H Li, A Markal, JA Balch, TJ Loftus… - Critical Care …, 2022 - journals.lww.com
OBJECTIVE: Despite its heterogeneous phenotypes, sepsis or life-threatening dysfunction in
response to infection is often treated empirically. Identifying patient subgroups with unique …