Efficacy of neutral and negatively charged liposome-loaded gentamicin on planktonic bacteria and biofilm communities

M Alhariri, MA Majrashi, AH Bahkali… - International journal …, 2017 - Taylor & Francis
We investigated the efficacy of liposomal gentamicin formulations of different surface
charges against Pseudomonas aeruginosa and Klebsiella oxytoca. The liposomal …

Eradication of methicillin-resistant Staphylococcus aureus infection by nanoliposomes loaded with gentamicin and oleic acid

DG Atashbeyk, B Khameneh, M Tafaghodi… - Pharmaceutical …, 2014 - Taylor & Francis
Abstract Context: Methicillin-resistant Staphylococcus aureus (MRSA) infection with its high
incidence is responsible for nosocomial infections. MRSA strains resistant to multiple …

Liposome-Encapsulated Tobramycin and IDR-1018 Peptide Mediated Biofilm Disruption and Enhanced Antimicrobial Activity against Pseudomonas aeruginosa

NM Alzahrani, RY Booq, AM Aldossary, AA Bakr… - Pharmaceutics, 2022 - mdpi.com
The inadequate eradication of pulmonary infections and chronic inflammation are significant
complications in cystic fibrosis (CF) patients, who usually suffer from persistent and frequent …

Antibacterial activity of liposomal gentamicin against Pseudomonas aeruginosa: a time–kill study

G Rukholm, C Mugabe, AO Azghani, A Omri - International journal of …, 2006 - Elsevier
Cystic fibrosis (CF) is a common and lethal genetic disorder with a carrier frequency of 1 in
29 Caucasians. Chronic respiratory infections with Pseudomonas aeruginosa are the …

[HTML][HTML] Liposomal drug delivery strategies to eradicate bacterial biofilms: Challenges, recent advances, and future perspectives

VK Panthi, KE Fairfull-Smith, N Islam - International Journal of …, 2024 - Elsevier
Typical antibiotic treatments are often ineffectual against biofilm-related infections since
bacteria residing within biofilms have developed various mechanisms to resist antibiotics. To …

Fusion between fluid liposomes and intact bacteria: study of driving parameters and in vitro bactericidal efficacy

Z Wang, Y Ma, H Khalil, R Wang, T Lu… - International journal …, 2016 - Taylor & Francis
Background Pseudomonas aeruginosa represents a good model of antibiotic resistance.
These organisms have an outer membrane with a low level of permeability to drugs that is …

Antibiotic-loaded lipid-based nanocarrier: A promising strategy to overcome bacterial infection

MAB Henostroza, GD Tavares, MN Yukuyama… - International Journal of …, 2022 - Elsevier
Abstract According to the World Health Organization (WHO) and Centers for Disease Control
and Prevention (CDC), bacterial infections are one of the greatest threats to global health …

The roles of lipid in anti-biofilm efficacy of lipid–polymer hybrid nanoparticles encapsulating antibiotics

WS Cheow, MW Chang, K Hadinoto - Colloids and surfaces A …, 2011 - Elsevier
Owing to their physical robustness, lipid–polymer hybrid nanoparticles are developed to
potentially replace liposomes, which possess high affinity towards biofilm cells, as antibiotic …

Lysozyme associated liposomal gentamicin inhibits bacterial biofilm

Y Hou, Z Wang, P Zhang, H Bai, Y Sun, J Duan… - International Journal of …, 2017 - mdpi.com
Bacteria on living or inert surfaces usually form biofilms which make them highly resistant to
antibiotics and immune clearance. Herein, we develop a simple approach to overcome the …

The effect of nanoliposomal formulations on Staphylococcus epidermidis biofilm

N Moghadas-Sharif, BS Fazly Bazzaz… - Drug Development …, 2015 - Taylor & Francis
Objective: The aim of the present study was to assess the in vitro antimicrobial activities of
nanoliposomal formulations loaded with vancomycin or/and rifampin against the biofilm …