Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders
S Kim, MJ Webster - Molecular psychiatry, 2011 - nature.com
Cytoarchitectural abnormalities have been described in the prefrontal cortex (PFC) of
subjects with psychiatric disorders. We explored the possible genetic causalities that may …
subjects with psychiatric disorders. We explored the possible genetic causalities that may …
Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders
S Kim, MJ Webster - Molecular psychiatry, 2010 - nature.com
Cytoarchitectural abnormalities have been described in the prefrontal cortex of subjects with
schizophrenia, bipolar disorder and depression. However, little is known about the gene …
schizophrenia, bipolar disorder and depression. However, little is known about the gene …
[HTML][HTML] The overlapping genetic architecture of psychiatric disorders and cortical brain structure
Both psychiatric vulnerability and cortical structure are shaped by the cumulative effect of
common genetic variants across the genome. However, the shared genetic underpinnings …
common genetic variants across the genome. However, the shared genetic underpinnings …
The general impact of haploinsufficiency on brain connectivity underlies the pleiotropic effect of neuropsychiatric CNVs
Background Resting-state functional MRI studies have provided critical insight into brain
networks involved in neuropsychiatric conditions (NPs) but only a few studies have …
networks involved in neuropsychiatric conditions (NPs) but only a few studies have …
Cross-disorder analysis of shared genetic components between cortical structures and major psychiatric disorders
Abstract Background and Hypothesis Although large-scale neuroimaging studies have
demonstrated similar patterns of structural brain abnormalities across major psychiatric …
demonstrated similar patterns of structural brain abnormalities across major psychiatric …
Overlap in genetic risk for cross-disorder vulnerability to mental disorders and genetic risk for altered subcortical brain volumes
Background There have been considerable recent advances in understanding the genetic
architecture of psychiatric disorders as well as the underlying neurocircuitry. However, there …
architecture of psychiatric disorders as well as the underlying neurocircuitry. However, there …
[HTML][HTML] Polygenic risk for five psychiatric disorders and cross-disorder and disorder-specific neural connectivity in two independent populations
Major psychiatric disorders, including attention deficit hyperactivity disorder (ADHD), autism
(AUT), bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SZ), are …
(AUT), bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SZ), are …
A genome-wide association study suggests novel loci associated with a schizophrenia-related brain-based phenotype
Patients with schizophrenia and their siblings typically show subtle changes of brain
structures, such as a reduction of hippocampal volume. Hippocampal volume is heritable …
structures, such as a reduction of hippocampal volume. Hippocampal volume is heritable …
Effects of eight neuropsychiatric copy number variants on human brain structure
Many copy number variants (CNVs) confer risk for the same range of neurodevelopmental
symptoms and psychiatric conditions including autism and schizophrenia. Yet, to date …
symptoms and psychiatric conditions including autism and schizophrenia. Yet, to date …
Psychiatric polygenic risk associates with cortical morphology and functional organization in aging
A Lee, M Shen, A Qiu - Translational Psychiatry, 2017 - nature.com
Common brain abnormalities in cortical morphology and functional organization are
observed in psychiatric disorders and aging, reflecting shared genetic influences. This …
observed in psychiatric disorders and aging, reflecting shared genetic influences. This …
相关搜索
- prefrontal cortex cytoarchitectural abnormalities
- psychiatric disorders cytoarchitectural abnormalities
- prefrontal cortex psychiatric disorders
- association analysis cytoarchitectural abnormalities
- prefrontal cortex association analysis
- association analysis psychiatric disorders
- prefrontal cortex expression profiles
- expression profiles psychiatric disorders
- expression profiles cytoarchitectural abnormalities
- psychiatric disorders independent populations
- psychiatric disorders neural connectivity
- psychiatric disorders polygenic risk
- psychiatric disorders brain structure
- psychiatric disorders cell biology
- correlation analysis cytoarchitectural abnormalities
- prefrontal cortex correlation analysis