An abnormal electrophysiological response in brain slices of the dentate gyrus from biopsy
material from patients surgicially treated for intractable epilepsy (46 57), exhibited …

In an epileptic rat model of generalized absence epilepsies, the genetic absence epilepsy
rats from Strasbourg (GAERS), simultaneous recordings of bilateral epidural …

Overexcitation of neuronal networks in some forebrain structures and pathological
synchronization of neuronal activity play crucial role in epileptic seizures. Seizure activity …

To elucidate the gating mechanism of the epileptic dentate gyrus on seizure-like input, we
investigated dentate gyrus field potentials and granule cell excitatory postsynaptic potentials …

Recordings of epileptiform burst activity in the CA1 region of the transverse rat hippocampal
slices were made with a 32-channel surface electrode array. The 200 μm interelectrode …

Spreading depolarization of cells in cerebral grey matter is characterized by massive ion
translocation, neuronal swelling and large changes in direct current-coupled voltage …

Repetitive synchronized neuronal discharging that lasts for seconds and even minutes in in
vitro brain slice preparations are important new models in experimental epilepsy. In …

Excessive synchronous neuronal activity is a defining feature of epileptic activity. We
previously characterized the properties of distinct glutamatergic and GABAergic …

1. The horizontal propagation of epileptiform discharges has been studied in slices of
neocortex treated with high concentrations of bicuculline methiodide, an antagonist of the …

Purpose: In vitro brain preparations have been used extensively to study the generation and
propagation of epileptiform activity. Transverse and longitudinal slices of the rodent …